Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies
Brain tumors are among the most challenging human tumors for which the mechanisms driving
progression and heterogeneity remain poorly understood. We combined single-cell RNA-…
progression and heterogeneity remain poorly understood. We combined single-cell RNA-…
In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes
Background Special AT-rich sequence-binding protein 2 is essential for the development of
cerebral cortex and key molecular node for the establishment of proper neural circuitry and …
cerebral cortex and key molecular node for the establishment of proper neural circuitry and …
Intron retention by a novel intronic mutation in DKC1 gene caused recurrent still birth and early death in a Chinese family
Q Guo, P Zhang, W Ying, Y Wang, J Zhu… - … Genetics & Genomic …, 2022 - Wiley Online Library
… death in a Chinese family - Guo - 2022 - Molecular Genetics & Genomic Medicine - Wiley
Online Library … Qiufang Guo … Qiufang Guo and Ping Zhang contributed equally to this work. …
Online Library … Qiufang Guo … Qiufang Guo and Ping Zhang contributed equally to this work. …
[HTML][HTML] A trial of lopinavir–ritonavir in adults hospitalized with severe Covid-19
…, X Wu, Q Ge, J He, H Zhan, F Qiu, L Guo… - New England journal …, 2020 - Mass Medical Soc
Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label …
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label …
[HTML][HTML] HeLa-CCL2 cell heterogeneity studied by single-cell DNA and RNA sequencing
W Hu, X Zhang, Q Guo, J Yang, Y Yang, S Wei, X Su - PLoS One, 2019 - journals.plos.org
The HeLa cells are the earliest and mostly used laboratory human cells for biomedical
particularly cancer research. They were derived from a patient’s cervical cancerous tissue, and …
particularly cancer research. They were derived from a patient’s cervical cancerous tissue, and …
Concurrent chemoradiotherapy vs radiotherapy alone in stage II nasopharyngeal carcinoma: phase III randomized trial
QY Chen, YF Wen, L Guo, H Liu… - Journal of the …, 2011 - academic.oup.com
Background Concurrent chemoradiotherapy (CCRT) has been shown to improve outcomes
for stage III–IV nasopharyngeal carcinoma (NPC) patients compared with radiotherapy (RT) …
for stage III–IV nasopharyngeal carcinoma (NPC) patients compared with radiotherapy (RT) …
[HTML][HTML] Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced …
SM Cao, Q Yang, L Guo, HQ Mai, HY Mo… - European journal of …, 2017 - Elsevier
Background The role of neoadjuvant chemotherapy (NACT) for locoregionally advanced
nasopharyngeal carcinoma (NPC) is unclear. We aimed to evaluate the feasibility and efficacy …
nasopharyngeal carcinoma (NPC) is unclear. We aimed to evaluate the feasibility and efficacy …
[PDF][PDF] Prospective study of tailoring whole-body dual-modality [18F] fluorodeoxyglucose positron emission tomography/computed tomography with plasma Epstein …
LQ Tang, QY Chen, W Fan, H Liu, L Zhang, L Guo… - J Clin Oncol, 2013 - academia.edu
Purpose To evaluate which patients with nasopharyngeal carcinoma (NPC) obtained the
greatest benefits from the detection of distant metastasis with [18F] fluorodeoxyglucose positron …
greatest benefits from the detection of distant metastasis with [18F] fluorodeoxyglucose positron …
[HTML][HTML] A genome-wide association study identifies six novel risk loci for primary biliary cholangitis
…, J Wu, Q Huang, J Han, W Xie, Z Sun, J Guo… - Nature …, 2017 - nature.com
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a strong hereditary
component. Here, we report a genome-wide association study that included 1,122 PBC cases …
component. Here, we report a genome-wide association study that included 1,122 PBC cases …
[HTML][HTML] Locoregional radiotherapy in patients with distant metastases of nasopharyngeal carcinoma at diagnosis
MY Chen, R Jiang, L Guo, X Zou, Q Liu… - Chinese journal of …, 2013 - ncbi.nlm.nih.gov
Systemic chemotherapy is the basic palliative treatment for metastatic nasopharyngeal
carcinoma (NPC); however, it is not known whether locoregional radiotherapy targeting the …
carcinoma (NPC); however, it is not known whether locoregional radiotherapy targeting the …