Three series of H 2 S donors based on NSAIDs were synthesized and characterized by 1 H-NMR,
IR and ESI-HRMS. The H 2 S-release abilities of all compounds were evaluated in the …

Atherosclerosis (AS), an important cause of high mortality of cardiovascular disease, involves
numerous pathophysiological processes, including endothelial cell damage, oxidative …

Host pathogen-recognition receptors detect nucleic acid from invading viruses and initiate a
series of signaling pathways that lead to the production of type I interferons (IFNs) and …

Background: Smooth muscle cells (SMC) play a critical role in atherosclerosis. The Aryl
hydrocarbon receptor (AHR) is an environment-sensing transcription factor that contributes to …

Rationale: The gene encoding TCF21 (transcription factor 21) has been linked to coronary
artery disease risk by human genome-wide association studies in multiple racial ethnic groups…

Background: Smooth muscle cells (SMCs) transition into a number of different phenotypes
during atherosclerosis, including those that resemble fibroblasts and chondrocytes, and make …

A mild and selective system comprising N-hydroxyphthalimide (NHPI) and Fe(NO3)3·9H2O
was developed for the oxidation of benzylic methylenes with an atmospheric pressure of …

A versatile Cu-catalyzed cross-coupling reaction to various unsymmetrical disulfanes has
been presented, from phthalimide-carried disulfur transfer reagents and commercially …

Atherosclerotic plaques consist mostly of smooth muscle cells (SMCs), and genes that
influence SMC phenotype can modulate coronary artery disease (CAD) risk. Allelic variation at …

Although numerous genetic loci have been associated with coronary artery disease (CAD)
with genome wide association studies, efforts are needed to identify the causal genes in …