User profiles for R Heer

Rakesh Heer

Verified email at ncl.ac.uk
Cited by 3427

[HTML][HTML] High-risk non-muscle-invasive bladder cancer—therapy options during intravesical BCG shortage

R Veeratterapillay, R Heer, MI Johnson, R Persad… - Current urology …, 2016 - Springer
Bladder cancer is the second commonest urinary tract malignancy with 70–80 % being non-muscle
invasive (NMIBC) at diagnosis. Patients with high-risk NMIBC (T1/Tis, with high grade…

The mutational landscape of human somatic and germline cells

…, CA Iacobuzio-Donahue, I Martincorena, R Heer… - Nature, 2021 - nature.com
Over the course of an individual’s lifetime, normal human cells accumulate mutations 1 . Here
we compare the mutational landscape in 29 cell types from the soma and germline using …

[HTML][HTML] Time to turn on the blue lights: a systematic review and meta-analysis of photodynamic diagnosis for bladder cancer

…, O Aboumarzouk, B Rai, L Vale, R Heer - European Urology Open …, 2021 - Elsevier
… Author contributions: Rakesh Heer had full access to all the data in the study and takes …
Financial disclosures: Rakesh Heer certifies that all conflicts of interest, including specific …

Can we deliver randomized trials of focal therapy in prostate cancer?

…, D Bottomley, W Cross, R Heer, R Kaplan… - Nature reviews Clinical …, 2014 - nature.com
Tissue-preserving focal therapies, such as brachytherapy, cryotherapy, high-intensity focused
ultrasound and photodynamic therapy, aim to target individual cancer lesions rather than …

An examination of a theory of embodied social presence in virtual worlds

…, JL Triplett, LM Hassall, ZJ Conde, R Heer - Decision …, 2011 - Wiley Online Library
In this article, we discuss and empirically examine the importance of embodiment, context,
and spatial proximity as they pertain to collaborative interaction and task completion in virtual …

The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer

…, C Dalgliesh, P Rajan, SM Nicol, S Fleming, R Heer… - Cancer research, 2008 - AACR
The androgen receptor (AR) is a member of the nuclear steroid hormone receptor family and
is thought to play an important role in the development of both androgen-dependent and …

[PDF][PDF] A unifying theory of branching morphogenesis

E Hannezo, CLGJ Scheele, M Moad, N Drogo, R Heer… - Cell, 2017 - cell.com
… depends only on the ratio of the annihilation radius to the characteristic duct length, R
for r = 0.1 without approximation (Figures S4E and S4F), as well as numerical integrations for …

Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis

…, SAC McDonald, S Kelly, JC Mathers, R Heer… - Nature cancer, 2020 - nature.com
Oxidative phosphorylation (OXPHOS) defects caused by somatic mitochondrial DNA mutations
increase with age in human colorectal epithelium and are prevalent in colorectal tumors, …

Granulomatous mastitis can mimic breast cancer on clinical, radiological or cytological examination: a cautionary tale

R Heer, J Shrimankar, CDM Griffith - The breast, 2003 - Elsevier
In both women and men, breast lumps are the most common presentation of breast cancer.
The following cases illustrate the pathological entity of granulomatous mastitis, which can …

The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover

…, D Alkharaif, J Stockley, R Heer… - Nucleic acids …, 2013 - academic.oup.com
… This allowed R 2 values and the slope of the standard curve to be calculated, so that
interexperimental variation could be taken into account. Screening with this experimental end point …