User profiles for R. A. Verdugo

Ricardo Verdugo

Assistant Professor of Human Genetics, Universidad de Chile
Verified email at u.uchile.cl
Cited by 2148

Genetic analysis of complex traits in the emerging Collaborative Cross

…, W Foulds-Mathes, RJ Buus, RA Verdugo… - Genome …, 2011 - genome.cshlp.org
The Collaborative Cross (CC) is a mouse recombinant inbred strain panel that is being
developed as a resource for mammalian systems genetics. Here we describe an experiment that …

Native American gene flow into Polynesia predating Easter Island settlement

…, EG Burchard, CR Gignoux, L Cifuentes, RA Verdugo… - Nature, 2020 - nature.com
The possibility of voyaging contact between prehistoric Polynesian and Native American
populations has long intrigued researchers. Proponents have pointed to the existence of New …

The genetic prehistory of the Andean highlands 7000 years BP though European contact

…, C Hofman, M Apata, M Moraga, RA Verdugo… - Science …, 2018 - science.org
The peopling of the Andean highlands above 2500 m in elevation was a complex process
that included cultural, biological, and genetic adaptations. Here, we present a time series of …

Paths and timings of the peopling of Polynesia inferred from genomic networks

…, S Huntsman, EG Burchard, CR Gignoux, RA Verdugo… - Nature, 2021 - nature.com
… Settlers also fanned out from Rarotonga northeast to the Society Islands (represented by
Tahiti in our dataset but also containing the culturally significant island Ra‘iātea) around ad …

[HTML][HTML] A second update on mapping the human genetic architecture of COVID-19

…, CL Vallerga, S van der Laan, RA Verdugo… - Nature, 2023 - nature.com
Investigating the role of host genetic factors in COVID-19 severity and susceptibility can
inform our understanding of the underlying biological mechanisms that influence adverse …

Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia

…, E Willerslev, E Llop, RA Verdugo… - Proceedings of the …, 2018 - National Acad Sciences
Patagonia was the last region of the Americas reached by humans who entered the continent
from Siberia ∼15,000–20,000 y ago. Despite recent genomic approaches to reconstruct …

chromPlot: visualization of genomic data in chromosomal context

KY Oróstica, RA Verdugo - Bioinformatics, 2016 - academic.oup.com
Visualizing genomic data in chromosomal context can help detecting errors in data processing
and may suggest new hypotheses to be tested. Here, we report a new tool for displaying …

[HTML][HTML] Graphical modeling of gene expression in monocytes suggests molecular mechanisms explaining increased atherosclerosis in smokers

RA Verdugo, T Zeller, M Rotival, PS Wild, T Münzel… - PloS one, 2013 - journals.plos.org
Smoking is a risk factor for atherosclerosis with reported widespread effects on gene
expression in circulating blood cells. We hypothesized that a molecular signature mediating the …

[HTML][HTML] Clinical and pulmonary function analysis in long-COVID revealed that long-term pulmonary dysfunction is associated with vascular inflammation pathways …

…, C Salomon, RA Verdugo… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Methods Patients with L-TPD were classified according to the results of their computer-tomography
(CT) scan and diffusing capacity of the lungs for carbon monoxide adjusted for …

[HTML][HTML] Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components

RA Verdugo, A Di Genova, L Herrera, M Moraga… - Biological research, 2020 - Springer
Background Current South American populations trace their origins mainly to three
continental ancestries, ie European, Amerindian and African. Individual variation in relative …