Fungal evolutionary genomics provides insight into the mechanisms of adaptive divergence in eukaryotes

…, DM De Vienne, RC Rodríguez De La Vega… - Molecular …, 2014 - Wiley Online Library
Fungi are ideal model organisms for dissecting the genomic bases of adaptive divergence
in eukaryotes. They have simple morphologies and small genomes, occupy contrasting, well‐…

K+ channel blockers: novel tools to inhibit T cell activation leading to specific immunosuppression

G Panyi, LD Possani, RCR De La Vega… - Current …, 2006 - ingentaconnect.com
During the last two decades since the identification and characterization of T cell potassium
channels great advances have been made in the understanding of the role of these …

Understanding adaptation, coevolution, host specialization, and mating system in castrating anther-smut fungi by combining population and comparative genomics

FE Hartmann, RC Rodríguez de la Vega… - Annual review of …, 2019 - annualreviews.org
Anther-smut fungi provide a powerful system to study host–pathogen specialization and
coevolution, with hundreds of Microbotryum species specialized on diverse Caryophyllaceae …

[HTML][HTML] Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones)

…, E Diego-Garcia, RC Rodríguez de la Vega… - BMC genomics, 2007 - Springer
Background Scorpions like other venomous animals posses a highly specialized organ that
produces, secretes and disposes the venom components. In these animals, the last …

Mycobacterial pan-genome analysis suggests important role of plasmids in the radiation of type VII secretion systems

…, RC Rodríguez de la Vega… - Genome Biology and …, 2016 - academic.oup.com
In mycobacteria, various type VII secretion systems corresponding to different ESX (ESAT-6
secretory) types, are contributing to pathogenicity, iron acquisition, and/or conjugation. In …

Evolutionary strata on young mating-type chromosomes despite the lack of sexual antagonism

…, RC Rodríguez de la Vega… - Proceedings of the …, 2017 - National Acad Sciences
Sex chromosomes can display successive steps of recombination suppression known as “evolutionary
strata,” which are thought to result from the successive linkage of sexually …

[HTML][HTML] Multiple convergent supergene evolution events in mating-type chromosomes

…, F Carpentier, RC Rodríguez de la Vega… - Nature …, 2018 - nature.com
Convergent adaptation provides unique insights into the predictability of evolution and
ultimately into processes of biological diversification. Supergenes (beneficial gene linkage) are …

Cytolytic and K+ channel blocking activities of β-KTx and scorpine-like peptides purified from scorpion venoms

…, EF Schwartz, RCR De La Vega… - Cellular and Molecular …, 2008 - Springer
Among the scorpion venom components whose function are poorly known or even show
contrasting pharmacological results are those called “orphan peptides”. The most widely …

Independent domestication events in the blue‐cheese fungus Penicillium roqueforti

…, A Feurtey, RC Rodríguez de la Vega… - Molecular …, 2020 - Wiley Online Library
Domestication provides an excellent framework for studying adaptive divergence. Using
population genomics and phenotypic assays, we reconstructed the domestication history of the …

Structure, Function, and Chemical Synthesis of Vaejovis mexicanus Peptide 24: A Novel Potent Blocker of Kv1.3 Potassium Channels of Human T Lymphocytes

…, RA Hernández-López, RC Rodríguez de la Vega… - Biochemistry, 2012 - ACS Publications
Animal venoms are rich sources of ligands for studying ion channels and other pharmacological
targets. Proteomic analyses of the soluble venom from the Mexican scorpion Vaejovis …