OBJECTIVE: To qualitatively review the literature of the past decade covering the epidemiology,
clinical characteristics, natural course, biology, and other correlates of early-onset major …

This article introduces and summarizes the goals of the symposium. It also provides an overview
of a conceptual framework for understanding adolescence, which emphasizes how the …

… Last, we suggest a re-evaluation and extension of the prevailing models of adolescent brain
development. We emphasize the lack of data supporting any simple view of frontal cortical …

This study examines important developmental differences in patterns of activation in the
prefrontal cortex during performance of a Go-No-Go paradigm using functional magnetic …

ContextMajor depressive disorder (MDD) that arises in adolescence impairs functioning
and is associated with suicide risk, but little is known about its continuity into adulthood.…

… specific neural systems) and human studies, to address the important but complex issues
regarding cognitive, emotional, and motivational changes directly linked to puberty [see Dahl …

There are several converging reasons to focus on sleep regulation in relation to healthy
adolescent development: (a) Sleep appears to be particularly important during periods of brain …

Throughout early development, a child spends more time asleep than in any waking activity.
Yet, the specific role of sleep in brain maturation is a complete mystery. In this article, the …

… increases in sensation-seeking, and a re-orientation of attention and motivational
salience towards … Crone, EA & Dahl, RE Understanding adolescence as a period of social–affective …

… these adolescent changes are part of a more general re-orientation of social behavior.
More … We consider how these motivational changes contribute to the broader social re-orientation …