User profiles for R. F. Laine

Romain F. Laine

University College London, MRC-LMCB
Verified email at ucl.ac.uk
Cited by 3139

NanoJ: a high-performance open-source super-resolution microscopy toolbox

RF Laine, KL Tosheva, N Gustafsson… - Journal of physics D …, 2019 - iopscience.iop.org
Super-resolution microscopy (SRM) has become essential for the study of nanoscale
biological processes. This type of imaging often requires the use of specialised image analysis …

TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines

…, A Charles-Orszag, JRW Conway, RF Laine… - Nature …, 2022 - nature.com
TrackMate is an automated tracking software used to analyze bioimages and is distributed
as a Fiji plugin. Here, we introduce a new version of TrackMate. TrackMate 7 is built to …

[HTML][HTML] Democratising deep learning for microscopy with ZeroCostDL4Mic

L von Chamier, RF Laine, J Jukkala, C Spahn… - Nature …, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can outperform
conventional image processing pipelines. Despite the enthusiasm and innovations fuelled …

Artificial intelligence for microscopy: what you should know

L von Chamier, RF Laine… - Biochemical Society …, 2019 - portlandpress.com
Artificial Intelligence based on Deep Learning (DL) is opening new horizons in biomedical
research and promises to revolutionize the microscopy field. It is now transitioning from the …

[HTML][HTML] Imaging in focus: an introduction to denoising bioimages in the era of deep learning

RF Laine, G Jacquemet, A Krull - The international journal of biochemistry & …, 2021 - Elsevier
Fluorescence microscopy enables the direct observation of previously hidden dynamic
processes of life, allowing profound insights into mechanisms of health and disease. However, …

Avoiding a replication crisis in deep-learning-based bioimage analysis

RF Laine, I Arganda-Carreras, R Henriques… - Nature …, 2021 - nature.com
Deep learning algorithms are powerful tools for analyzing, restoring and transforming
bioimaging data. One promise of deep learning is parameter-free one-click image analysis with …

[HTML][HTML] Structural analysis of herpes simplex virus by optical super-resolution imaging

RF Laine, A Albecka, S Van De Linde, EJ Rees… - Nature …, 2015 - nature.com
Herpes simplex virus type-1 (HSV-1) is one of the most widespread pathogens among
humans. Although the structure of HSV-1 has been extensively investigated, the precise …

[PDF][PDF] RNA docking and local translation regulate site-specific axon remodeling in vivo

…, JM Cioni, R Cagnetta, B Turner-Bridger, RF Laine… - Neuron, 2017 - cell.com
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein
synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major …

Bringing TrackMate into the era of machine-learning and deep-learning

…, A Charles-Orszag, JRW Conway, RF Laine… - BioRxiv, 2021 - biorxiv.org
TrackMate is an automated tracking software used to analyze bioimages and distributed as a
Fiji plugin. Here we introduce a new version of TrackMate rewritten to improve performance …

[HTML][HTML] DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches

C Spahn, E Gómez-de-Mariscal, RF Laine… - Communications …, 2022 - nature.com
This work demonstrates and guides how to use a range of state-of-the-art artificial neural-networks
to analyse bacterial microscopy images using the recently developed …