User profiles for R. J. Dobson

Professor Richard Dobson

Group lead and Professor in Bioinformatics, Kings College London
Verified email at kcl.ac.uk
Cited by 30467

Worm control and anthelmintic resistance: adventures with a model

EH Barnes, RJ Dobson, IA Barger - Parasitology Today, 1995 - cell.com
There are three common questions asked of parasitologists timing of treatment, drug efficacy,
life expectancy and about anthelmintic resistance. Does it matter? How do you fecundity of …

[HTML][HTML] World Association for the Advancement of Veterinary Parasitology (WAAVP) guideline for diagnosing anthelmintic resistance using the faecal egg count …

…, PR Torgerson, JS Gilleard, RJ Dobson… - Veterinary …, 2023 - Elsevier
The faecal egg count reduction test (FECRT) remains the method of choice for establishing
the efficacy of anthelmintic compounds in the field, including the diagnosis of anthelmintic …

Management of anthelmintic resistance: inheritance of resistance and selection with persistent drugs

RJ Dobson, L Lejambre, JH Gill - International journal for parasitology, 1996 - Elsevier
… In this paper the model of Barnes & Dobson (1990) is used to examine the impact of a …
We report here modifications to the model of Barnes & Dobson (1990) so that the relative …

[PDF][PDF] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

…, M Tobin, M Falchi, K Ahmadi, RJ Dobson… - The American Journal of …, 2008 - cell.com
Many common diseases are accompanied by disturbances in biochemical traits. Identifying
the genetic determinants could provide novel insights into disease mechanisms and reveal …

[HTML][HTML] SLC2A9 is a high-capacity urate transporter in humans

…, P Howard, S Shaw-Hawkins, RJ Dobson… - PLoS …, 2008 - journals.plos.org
Background Serum uric acid levels in humans are influenced by diet, cellular breakdown,
and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, …

Natural language processing to extract symptoms of severe mental illness from clinical text: the Clinical Record Interactive Search Comprehensive Data Extraction …

…, M Ball, G Gorrell, A Roberts, RJ Dobson… - BMJ open, 2017 - bmjopen.bmj.com
Objectives We sought to use natural language processing to develop a suite of language
models to capture key symptoms of severe mental illness (SMI) from clinical text, to facilitate the …

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

…, P Howard, A Onipinla, RJ Dobson… - Human molecular …, 2009 - academic.oup.com
Hypertension is a complex disease that affects a large proportion of adult population. Although
approximately half of the inter-individual variance in blood pressure (BP) level is heritable…

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

…, PC Dubois, CA Mein, RJ Dobson… - Human molecular …, 2010 - academic.oup.com
Many disease-associated variants identified by genome-wide association (GWA) studies
are expected to regulate gene expression. Allele-specific expression (ASE) quantifies …

[PDF][PDF] Blood pressure loci identified with a gene-centric array

…, MJ Brown, JM Connell, RJ Dobson… - The American Journal of …, 2011 - cell.com
Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies
have identified 47 distinct genetic variants robustly associated with BP, but collectively …

Identification of Major Outer Surface Proteins of Streptococcus agalactiae

…, R Wilson, PK Pribul, ZN Younes, RJ Dobson… - Infection and …, 2002 - Am Soc Microbiol
To identify the major outer surface proteins of Streptococcus agalactiae (group B streptococcus),
a proteomic analysis was undertaken. An extract of the outer surface proteins was …