User profiles for R. J. Sinke
richard sinkeProfessor of Genome Analysis, dept. Genetics (MGE), University Medical Center Groningen Verified email at ziggo.nl Cited by 9147 |
An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia
Several lines of evidence, including expression analyses, brain imaging and genetic studies
suggest that the integrity of myelin is disturbed in schizophrenia patients. In this study, we …
suggest that the integrity of myelin is disturbed in schizophrenia patients. In this study, we …
Dystonia in children and adolescents: a systematic review and a new diagnostic algorithm
Early aetiological diagnosis is of paramount importance for childhood dystonia because
some of the possible underlying conditions are treatable. Numerous genetic and non-genetic …
some of the possible underlying conditions are treatable. Numerous genetic and non-genetic …
Targeted next‐generation sequencing can replace Sanger sequencing in clinical diagnostics
Mutation detection through exome sequencing allows simultaneous analysis of all coding
sequences of genes. However, it cannot yet replace S anger sequencing ( SS ) in diagnostics …
sequences of genes. However, it cannot yet replace S anger sequencing ( SS ) in diagnostics …
Spinocerebellar ataxias in the Netherlands: prevalence and age at onset variance analysis
BPC Van de Warrenburg, RJ Sinke… - Neurology, 2002 - AAN Enterprises
Background: International prevalence estimates of autosomal dominant cerebellar ataxias (ADCA)
vary from 0.3 to 2.0 per 100,000. The prevalence of ADCA in the Netherlands is …
vary from 0.3 to 2.0 per 100,000. The prevalence of ADCA in the Netherlands is …
Mendelian disorders of high-density lipoprotein metabolism
High-density lipoproteins (HDLs) are a highly heterogeneous and dynamic group of the
smallest and densest lipoproteins present in the circulation. This review provides the current …
smallest and densest lipoproteins present in the circulation. This review provides the current …
[PDF][PDF] A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q
…, WB Gunning, PL Pearson, RJ Sinke - The American Journal of …, 2003 - cell.com
A genome scan was performed on 164 Dutch affected sib pairs (ASPs) with attention-deficit/hyperactivity
disorder (ADHD). All subjects were white and of Dutch descent and were …
disorder (ADHD). All subjects were white and of Dutch descent and were …
Meta‐analysis of genome‐wide linkage scans of attention deficit hyperactivity disorder
…, H Schäfer, J Sergeant, RJ Sinke… - American Journal of …, 2008 - Wiley Online Library
Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is
well established. Seven independent genome‐wide linkage scans have been performed to …
well established. Seven independent genome‐wide linkage scans have been performed to …
Titin gene mutations are common in families with both peripartum cardiomyopathy and dilated cardiomyopathy
Aim Peripartum cardiomyopathy (PPCM) can be an initial manifestation of familial dilated
cardiomyopathy (DCM). We aimed to identify mutations in families that could underlie their …
cardiomyopathy (DCM). We aimed to identify mutations in families that could underlie their …
[HTML][HTML] Natural fibre reinforced sheet moulding compound
B Van Voorn, HHG Smit, RJ Sinke… - Composites part A: Applied …, 2001 - Elsevier
This paper describes a newly developed system, which enables utilisation of short flax
fibres for SMC (Sheet Moulding Compound) production. It is shown that by using an evenly …
fibres for SMC (Sheet Moulding Compound) production. It is shown that by using an evenly …
[PDF][PDF] Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined …
… RJ Sinke … Compr Psychiatry 32:73–82 Clarke AR, Barry RJ, McCarthy R, Selikowitz M,
Clarke DC, Croft RJ (2003) EEG activity in girls with attention-deficit/ hyperactivity disorder. Clin …
Clarke DC, Croft RJ (2003) EEG activity in girls with attention-deficit/ hyperactivity disorder. Clin …