Characterizing VIP neurons in the barrel cortex of VIPcre/tdTomato mice reveals layer-specific differences
A Prönneke, B Scheuer, RJ Wagener, M Möck… - Cerebral …, 2015 - academic.oup.com
Neocortical GABAergic interneurons have a profound impact on cortical circuitry and its
information processing capacity. Distinct subgroups of inhibitory interneurons can be …
information processing capacity. Distinct subgroups of inhibitory interneurons can be …
[PDF][PDF] Loss of BAF (mSWI/SNF) complexes causes global transcriptional and chromatin state changes in forebrain development
…, M Pirouz, C Kerimoglu, L Pham, RJ Wagener… - Cell reports, 2015 - cell.com
BAF (Brg/Brm-associated factors) complexes play important roles in development and are
linked to chromatin plasticity at selected genomic loci. Nevertheless, a full understanding of …
linked to chromatin plasticity at selected genomic loci. Nevertheless, a full understanding of …
[HTML][HTML] Parvalbumin-and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells
…, M Möck, M Feyerabend, J Guy, RJ Wagener… - Nature …, 2016 - nature.com
Disinhibition of cortical excitatory cell gate information flow through and between cortical
columns. The major contribution of Martinotti cells (MC) is providing dendritic inhibition to …
columns. The major contribution of Martinotti cells (MC) is providing dendritic inhibition to …
[HTML][HTML] TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus
…, A Awasthi, MA Stahlberg, RJ Wagener… - Nature …, 2017 - nature.com
TRPV1 is an ion channel activated by heat and pungent agents including capsaicin, and
has been extensively studied in nociception of sensory neurons. However, the location and …
has been extensively studied in nociception of sensory neurons. However, the location and …
[HTML][HTML] Heterogeneous fates of simultaneously-born neurons in the cortical ventricular zone
E Magrinelli, N Baumann, RJ Wagener, C Glangetas… - Scientific reports, 2022 - nature.com
Neocortical excitatory neurons belong to diverse cell types, which can be distinguished by
their dates of birth, laminar location, connectivity, and molecular identities. During …
their dates of birth, laminar location, connectivity, and molecular identities. During …
The somatosensory cortex of reeler mutant mice shows absent layering but intact formation and behavioral activation of columnar somatotopic maps
Sensory information acquired via the large facial whiskers is processed and relayed in the
whisker-to-barrel pathway, which shows multiple somatotopic maps of the receptor periphery. …
whisker-to-barrel pathway, which shows multiple somatotopic maps of the receptor periphery. …
[HTML][HTML] A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
L Hai, DC Hoffmann, RJ Wagener, DD Azorin… - Nature …, 2024 - nature.com
Tumor microtubes (TMs) connect glioma cells to a network with considerable relevance for
tumor progression and therapy resistance. However, the determination of TM-…
tumor progression and therapy resistance. However, the determination of TM-…
Persistence of Functional Sensory Maps in the Absence of Cortical Layers in the Somsatosensory Cortex of Reeler Mice
J Guy, RJ Wagener, M Möck, JF Staiger - Cerebral cortex, 2015 - academic.oup.com
In rodents, layer IV of the primary somatosensory cortex contains the barrel field, where
individual, large facial whiskers are represented as a dense cluster of cells. In the reeler mouse, …
individual, large facial whiskers are represented as a dense cluster of cells. In the reeler mouse, …
Thalamocortical Connections Drive Intracortical Activation of Functional Columns in the Mislaminated Reeler Somatosensory Cortex
RJ Wagener, M Witte, J Guy, N Mingo-Moreno… - Cerebral …, 2016 - academic.oup.com
Neuronal wiring is key to proper neural information processing. Tactile information from the
rodent's whiskers reaches the cortex via distinct anatomical pathways. The lemniscal …
rodent's whiskers reaches the cortex via distinct anatomical pathways. The lemniscal …
Selective inactivation of reelin in inhibitory interneurons leads to subtle changes in the dentate gyrus but leaves cortical layering and behavior unaffected
J Pahle, M Muhia, RJ Wagener, A Tippmann… - Cerebral …, 2020 - academic.oup.com
Reelin is an extracellular matrix protein, known for its dual role in neuronal migration during
brain development and in synaptic plasticity at adult stages. During the perinatal phase, …
brain development and in synaptic plasticity at adult stages. During the perinatal phase, …