User profiles for R. L. Reinhardt
R. Lee ReinhardtNational Jewish Health and University of Colorado Verified email at njhealth.org Cited by 17428 |
In vivo activation of antigen-specific CD4 T cells
Physical detection of antigen-specific CD4 T cells has revealed features of the in vivo
immune response that were not appreciated from in vitro studies. In vivo, antigen is initially …
immune response that were not appreciated from in vitro studies. In vivo, antigen is initially …
The differential expression of IL-4 and IL-13 and its impact on type-2 immunity
K Bao, RL Reinhardt - Cytokine, 2015 - Elsevier
Allergic disease represents a significant global health burden, and disease incidence continues
to rise in urban areas of the world. As such, a better understanding of the basic immune …
to rise in urban areas of the world. As such, a better understanding of the basic immune …
Pluripotency of mesenchymal stem cells derived from adult marrow
Y Jiang, BN Jahagirdar, RL Reinhardt, RE Schwartz… - Nature, 2002 - nature.com
We report here that cells co-purifying with mesenchymal stem cells—termed here multipotent
adult progenitor cells or MAPCs—differentiate, at the single cell level, not only into …
adult progenitor cells or MAPCs—differentiate, at the single cell level, not only into …
Visualizing the generation of memory CD4 T cells in the whole body
It is thought that immunity depends on naļve CD4 T cells that proliferate in response to
microbial antigens 1 , 2 , 3 , 4 , differentiate into memory cells that produce anti-microbial …
microbial antigens 1 , 2 , 3 , 4 , differentiate into memory cells that produce anti-microbial …
Systemically dispersed innate IL-13–expressing cells in type 2 immunity
…, HE Liang, BM Sullivan, RL Reinhardt… - Proceedings of the …, 2010 - National Acad Sciences
Type 2 immunity is a stereotyped host response to allergens and parasitic helminths that is
sustained in large part by the cytokines IL-4 and IL-13. Recent advances have called …
sustained in large part by the cytokines IL-4 and IL-13. Recent advances have called …
Cytokine-secreting follicular T cells shape the antibody repertoire
RL Reinhardt, HE Liang, RM Locksley - Nature immunology, 2009 - nature.com
High-affinity antibodies are critical for host protection and underlie successful vaccines. The
generation of such antibodies requires T cell–dependent help, which mediates germinal …
generation of such antibodies requires T cell–dependent help, which mediates germinal …
[PDF][PDF] Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
Peptide:MHC II complexes derived from a fluorescent antigen were detected in vivo to
identify the cells that present subcutaneously injected antigen to CD4 T cells. Skin-derived …
identify the cells that present subcutaneously injected antigen to CD4 T cells. Skin-derived …
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
DB Stetson, M Mohrs, RL Reinhardt, JL Baron… - The Journal of …, 2003 - rupress.org
Natural killer (NK) and NK T cells are tissue lymphocytes that secrete cytokines rapidly upon
stimulation. Here, we show that these cells maintain distinct patterns of constitutive cytokine …
stimulation. Here, we show that these cells maintain distinct patterns of constitutive cytokine …
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity
HE Liang, RL Reinhardt, JK Bando, BM Sullivan… - Nature …, 2012 - nature.com
Interleukin 4 (IL-4) and IL-13 are critical for responses to parasitic helminthes. We used
genetically engineered reporter mice to assess the temporal and spatial production of these …
genetically engineered reporter mice to assess the temporal and spatial production of these …
T helper cell effector fates—who, how and where?
RL Reinhardt, SJ Kang, HE Liang… - Current opinion in …, 2006 - Elsevier
CD4 helper T cells functionally organize the host immune response by elaborating cytokines,
often in patterns that have overlapping effects on other cells. Much interest centers on …
often in patterns that have overlapping effects on other cells. Much interest centers on …