Through direct signals to the nucleus mediated by the glucocorticoid receptor, exogenous
glucocorticoids impact a broad array of cellular functions. DNA binding of the glucocorticoid …

Newfound relatives of the classical Fc receptors (FcR) have been provisionally named the
Fc receptor homologs (FcRH). The recent identification of eight human and six mouse FcRH …

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by a
loss of tolerance to self-antigens and the production of high titers of serum autoantibodies. …

Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with
complex etiology but strong clustering in families (λ S = ∼30). We performed a genome-wide …

The risk of cancer was ascertained in 136 women with sicca syndrome followed at the
National Institutes of Health (NIH). Seven patients developed non-Hodgkin's lymphoma from 6 …

Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

Increased levels of B lymphocyte stimulator (BLyS) are associated with systemic
autoimmunity in animal models of spontaneous autoimmune disease, and transgenic animals …

… Kimberly. 1996. FcRIIIB alleles predict renal dysfunction in Wegeners Granulomatosis (WG). …
Edberg, JC, and RP Kimberly. 1992. Receptor specific probes for the study of individual Fc …

A novel anti-human DR5 monoclonal antibody, TRA-8, induces apoptosis of most tumor
necrosis factor-related apoptosis-inducing ligand (TRAIL)-sensitive tumor cells both in vitro and …

Many tumor cells shed specialized membrane vesicles known as exosomes. In this study, we
show that pretreatment of mice with exosomes produced by TS/A or 4T. 1 murine mammary …