Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
…, MJ Aryee, A Toubaji, DM Esopi, R Albadine… - Nature …, 2010 - nature.com
DNA double-strand breaks (DSBs) can lead to the development of genomic rearrangements,
which are hallmarks of cancer. Fusions between TMPRSS2, encoding the transmembrane …
which are hallmarks of cancer. Fusions between TMPRSS2, encoding the transmembrane …
Xp11 translocation renal cell carcinoma (RCC): extended immunohistochemical profile emphasizing novel RCC markers
…, J Hicks, AM De Marzo, R Albadine… - The American journal …, 2010 - journals.lww.com
Xp11 translocation renal cell carcinoma (RCC) harbor various TFE3 gene fusions, and are
known to underexpress epithelial immunohistochemical (IHC) markers such as cytokeratin …
known to underexpress epithelial immunohistochemical (IHC) markers such as cytokeratin …
Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas
A Chaux, R Albadine, A Toubaji, J Hicks… - The American journal …, 2011 - journals.lww.com
… Nuclei in each TMA spot were classified in 1 of the following categories: (1) negative for
TMPRSS2-ERG fusion: nucleus with 2 pairs of juxtaposed red (R) and green (G) signals forming …
TMPRSS2-ERG fusion: nucleus with 2 pairs of juxtaposed red (R) and green (G) signals forming …
PAX8 (+)/p63 (−) immunostaining pattern in renal collecting duct carcinoma (CDC): a useful immunoprofile in the differential diagnosis of CDC versus urothelial …
R Albadine, L Schultz, P Illei, D Ertoy… - The American journal …, 2010 - journals.lww.com
Background Collecting duct carcinoma (CDC) is a relatively rare but aggressive type of
renal malignancy with variable morphologic features. One of the World Health Organization …
renal malignancy with variable morphologic features. One of the World Health Organization …
[HTML][HTML] Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer
…, N Gonzalez-Roibon, L Schultz, R Albadine… - Modern pathology, 2012 - Elsevier
PTEN (phosphatase and tensin homolog on chromosome 10) is one of the most frequently
lost tumor suppressor genes in human cancers and it has been described in more than two-…
lost tumor suppressor genes in human cancers and it has been described in more than two-…
17, 18-Epoxyeicosatetraenoic Acid Targets PPARγ and p38 Mitogen–Activated Protein Kinase to Mediate Its Anti-inflammatory Effects in the Lung: Role of soluble …
C Morin, M Sirois, V Échavé, R Albadine… - American journal of …, 2010 - atsjournals.org
This study sought to assess putative pathways involved in the anti-inflammatory effects of 17,18-epoxyeicosatetraenoic
acid (17,18-EpETE), as measured by a decrease in the …
acid (17,18-EpETE), as measured by a decrease in the …
[HTML][HTML] Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors
…, S Jadallah, A Toubaji, N Nonomura, R Albadine… - Modern …, 2008 - nature.com
… was present between DNMT1 status in IGCNU and associated seminomas (r=0.14; P=0.57,
pairwise) nor associated nonseminomatous germ cell tumors (r=0.09; P=0.84, pairwise). …
pairwise) nor associated nonseminomatous germ cell tumors (r=0.09; P=0.84, pairwise). …
High epidermal growth factor receptor immunohistochemical expression in urothelial carcinoma of the bladder is not associated with EGFR mutations in exons 19 and …
Epidermal growth factor receptor (EGFR) is a member of the erbB tyrosine kinase family
reported to be overexpressed in a variety of solid malignancies. Mutations in exons 19 to 21 of …
reported to be overexpressed in a variety of solid malignancies. Mutations in exons 19 to 21 of …
[HTML][HTML] Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer
…, M Trotter, HS Sekhon, R Albadine… - Journal of Thoracic …, 2014 - Elsevier
Introduction Fluorescence in situ hybridization (FISH) is currently the standard for diagnosing
anaplastic lymphoma kinase (ALK)-rearranged (ALK+) lung cancers for ALK inhibitor …
anaplastic lymphoma kinase (ALK)-rearranged (ALK+) lung cancers for ALK inhibitor …
Immunoexpression status and prognostic value of mTOR and hypoxia-induced pathway members in primary and metastatic clear cell renal cell carcinomas
L Schultz, A Chaux, R Albadine, J Hicks… - The American journal …, 2011 - journals.lww.com
The need for effective targeted therapies for renal cell carcinomas (RCCs) has fueled the
interest for understanding molecular pathways involved in the oncogenesis of kidney tumors. …
interest for understanding molecular pathways involved in the oncogenesis of kidney tumors. …