Mass spectrometry has become the method of choice for the qualitative and quantitative
characterization of protein mixtures isolated from all kinds of living organisms. The raw data in …

Individual resources can join ProteomeXchange by implementing the ProteomeXchange
data submission and dissemination guidelines, and metadata requirements. In the current …

Nerve growth factor (NGF) and its precursor (proNGF) are primarily considered as regulators
of neuronal function that induce their responses via the tyrosine kinase receptor TrkA and …

A high resolution gel electrophoresis of histone is described, capable of distinguishing
between histone fractions whose mobilities differ by as little as 1%. Under the conditions of pH …

Using enrichment strategies many research groups are routinely producing large data sets
of post-translationally modified peptides for proteomic analysis using tandem mass …

The hyperacetylation of histones due to treatment of cultured cells wlth sodium butyrate has
been studied. The hyperacetylation is due to Inhibition of histone deacetylase. Other short …

O-GlcNAc is a widespread dynamic carbohydrate modification of cytosolic and nuclear
proteins with features analogous to phosphorylation. O-GlcNAc acts critically in many cellular …

In order to identify and compare the protein content of very low quantity samples of high
complexity, a protocol has been established that combines the differential profiling strength of a …

Purpose Biologic heterogeneity is a feature of diffuse large B-cell lymphoma (DLBCL), and
the existence of a subgroup with poor prognosis and phenotypic proximity to Burkitt …

We used an allelogenic Cre/loxP gene targeting strategy in mice to determine the role of
cytosolic phosphoenolpyruvate carboxykinase (PEPCK) in hepatic energy metabolism. Mice …