Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study

…, H Cheinquer, CJ Chen, RN Chien… - The lancet …, 2017 - thelancet.com
Background The 69th World Health Assembly approved the Global Health Sector Strategy
to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the …

Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study

…, M Buti, HLY Chan, A Chaudhry, RN Chien… - The lancet …, 2018 - thelancet.com
Background The 69th World Health Assembly approved the Global Health Sector Strategy
to eliminate viral hepatitis by 2030. Although no virological cure exists for hepatitis B virus (…

Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study

…, ME Cheon, CH Chien, RN Chien… - The Lancet …, 2022 - thelancet.com
Background Since the release of the first global hepatitis elimination targets in 2016, and until
the COVID-19 pandemic started in early 2020, many countries and territories were making …

[HTML][HTML] A one-year trial of lamivudine for chronic hepatitis B

CL Lai, RN Chien, NWY Leung, TT Chang… - … England Journal of …, 1998 - Mass Medical Soc
Background and Methods In preliminary trials, lamivudine, an oral nucleoside analogue, has
shown promise for the treatment of chronic hepatitis B. We conducted a one-year, double-…

[HTML][HTML] Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

…, DS Chen, HL Chen, PJ Chen, RN Chien… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

On the connection assignment problem of diagnosable systems

FP Preparata, G Metze, RT Chien - IEEE Transactions on …, 1967 - ieeexplore.ieee.org
This paper treats the problem of automatic fault diagnosis for systems with multiple faults.
The system is decomposed into n units u 1 , u 2 , . . . , u n , where a unit is a well-identifiable …

Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update

…, JH Kao, T Piratvisuth, HLY Chan, RN Chien… - Hepatology …, 2012 - Springer
Large volume of new data on the natural history and treatment of chronic hepatitis B virus (HBV)
infection have become available since 2008. These include further studies in …

Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B

…, TT Chang, R Guan, DI Tai, KY Ng, RN Chien… - Gastroenterology, 2000 - Elsevier
Background & Aims: One-year lamivudine therapy significantly suppressed hepatitis B virus
(HBV) replication, improved hepatic necroinflammatory activity, and prevented progression …

Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis Be antigen seroconversion rates: results after 3 years of therapy

…, JC Dent, S Edmundson, LD Condreay, RN Chien… - Hepatology, 2001 - journals.lww.com
A study in Chinese patients with chronic hepatitis B showed that treatment with lamivudine
for 1 year significantly improves liver histology and enhances hepatitis B e antigen (HBeAg) …

Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B

YS Hsu, RN Chien, CT Yeh, IS Sheen, HY Chiou… - Hepatology, 2002 - Elsevier
During the course of chronic hepatitis B virus (HBV) infection, hepatitis B e antigen (HBeAg)
seroconversion to its antibody (anti-HBe) often coincides with normalization of liver …