Success rates for genomic analyses of highly heterogeneous disorders can be greatly
improved if a large cohort of patient data is assembled to enhance collective capabilities for …

Interest in human mitochondrial genetic data is constantly increasing among both clinicians
and researchers, due to the involvement of mitochondrial DNA (mtDNA) in a number of …

The HmtDB resource hosts a database of human mitochondrial genome sequences from
individuals with healthy and disease phenotypes. The database is intended to support both …

Renal oncocytomas are rare benign tumors of the kidney and characterized by a deficient
complex I (CI) enzyme activity of the oxidative phosphorylation (OXPHOS) system caused by …

… We therefore performed a correlation analysis of proteome and transcriptome data and found
a high overall correlation between protein and mRNA levels (r = 0.671) similar to the value …

Papillary renal cell carcinoma (pRCC) is a malignant kidney cancer with a prevalence of 7–20%
of all renal tumors. Proteome and metabolome profiles of 19 pRCC and patient-matched …

Glioblastoma multiforme (GBM) is the most malignant brain cancer in adults, with a poor
prognosis, whose molecular stratification still represents a challenge in pathology and clinics. …

… Statistical analysis was performed using R (version 3.6.1) including R packages of data.table
for data cleaning and management, tidyr for data clean-up, and ggplot2 for data …

Background Neuroblastoma, a tumor of the developing sympathetic nervous system, is a
common childhood neoplasm that is often lethal. Mitochondrial DNA (mtDNA) mutations have …

Relationship between coronary plaque morphology of the left anterior descending artery and
12 months clinical outcome: the CLIMA study | European Heart Journal | Oxford Academic …