User profiles for R. Dutzler
 | Raimund DutzlerUniversity of Zurich Verified email at bioc.uzh.ch Cited by 8930 |
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
… -to-parameter ratio and a further drop of R free (30.2%) and R cryst (29.0%). The refined …
The final model has agreement factors R free and R cryst of 28.8% and 25.5%, respectively, …
The final model has agreement factors R free and R cryst of 28.8% and 25.5%, respectively, …
Gating the selectivity filter in ClC chloride channels
R Dutzler, EB Campbell, R MacKinnon - Science, 2003 - science.org
… R free was monitored throughout the refinement. The final model contains 13,224 protein …
The same set of reflections was set aside for the calculation of R free in the wild-type and …
The same set of reflections was set aside for the calculation of R free in the wild-type and …
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
RJC Hilf, R Dutzler - Nature, 2008 - nature.com
… of the University of Zürich for help with mass spectrometry, R. MacKinnon for comments
on the manuscript and members of the Dutzler laboratory for help in all stages of the project. …
on the manuscript and members of the Dutzler laboratory for help in all stages of the project. …
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
RJC Hilf, R Dutzler - Nature, 2009 - nature.com
… of the University of Zurich for help with mass spectrometry, R. MacKinnon for comments
on the manuscript and members of the Dutzler laboratory for help in all stages of the project. …
on the manuscript and members of the Dutzler laboratory for help in all stages of the project. …
X-ray structure of a calcium-activated TMEM16 lipid scramblase
JD Brunner, NK Lim, S Schenck, A Duerst, R Dutzler - Nature, 2014 - nature.com
… R and R free were monitored throughout. R free was calculated by selecting 5% of the … The
final model (CF1) contains 654 out of 735 residues per subunit, has R/R free values of 23.8% …
final model (CF1) contains 654 out of 735 residues per subunit, has R/R free values of 23.8% …
Structural basis for phospholipid scrambling in the TMEM16 family
JD Brunner, S Schenck, R Dutzler - Current opinion in structural biology, 2016 - Elsevier
… Author links open overlay panel Janine D Brunner 1 , Stephan Schenck 1 , Raimund
Dutzler … Dutzler … Yu, SE Gabriel, HC Hartzell, R. Tarran …
Dutzler … Dutzler … Yu, SE Gabriel, HC Hartzell, R. Tarran …
Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
…, V Kalienkova, AKM Lam, Y Neldner, R Dutzler - Nature, 2017 - nature.com
The calcium-activated chloride channel TMEM16A is a ligand-gated anion channel that
opens in response to an increase in intracellular Ca 2+ concentration 1 , 2 , 3 . The protein is …
opens in response to an increase in intracellular Ca 2+ concentration 1 , 2 , 3 . The protein is …
[HTML][HTML] Alternative chloride transport pathways as pharmacological targets for the treatment of cystic fibrosis
Cystic fibrosis is a hereditary disease that originates from mutations in the epithelial chloride
channel CFTR. Whereas established therapies for the treatment of cystic fibrosis target …
channel CFTR. Whereas established therapies for the treatment of cystic fibrosis target …
Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport
Members of the SLC11 (NRAMP) family transport iron and other transition-metal ions across
cellular membranes. These membrane proteins are present in all kingdoms of life with a …
cellular membranes. These membrane proteins are present in all kingdoms of life with a …
Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family
… R and R free were monitored throughout. R free was calculated by selection of 5% of the …
All members of the Dutzler laboratory are acknowledged for help in all stages of the project. …
All members of the Dutzler laboratory are acknowledged for help in all stages of the project. …