Prostaglandins, arachidonic acid, and inflammation
FA Kuehl Jr, RW Egan - Science, 1980 - science.org
The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological
agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE 2 , …
agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE 2 , …
MRI findings in Susac's syndrome
JO Susac, FR Murtagh, RA Egan, JR Berger, R Bakshi… - Neurology, 2003 - AAN Enterprises
Background: Susac syndrome (SS) is a self-limited syndrome, presumably autoimmune,
consisting of a clinical triad of encephalopathy, branch retinal artery occlusions, and hearing …
consisting of a clinical triad of encephalopathy, branch retinal artery occlusions, and hearing …
[HTML][HTML] Th2 cytokines and asthma the role of interleukin-5 in allergic eosinophilic disease
…, SP Umland, FM Cuss, RW Chapman, RW Egan - Respiratory …, 2001 - Springer
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation
and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective …
and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective …
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
…, A Pedan, MR Danzig, SP Umland, RW Egan… - Nature, 2002 - nature.com
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing,
wheezing and breathlessness. Although environmental factors such as allergen exposure …
wheezing and breathlessness. Although environmental factors such as allergen exposure …
Metagenomic discovery of biomass-degrading genes and genomes from cow rumen
The paucity of enzymes that efficiently deconstruct plant polysaccharides represents a major
bottleneck for industrial-scale conversion of cellulosic biomass into biofuels. Cow rumen …
bottleneck for industrial-scale conversion of cellulosic biomass into biofuels. Cow rumen …
[PDF][PDF] A landscape of pharmacogenomic interactions in cancer
…, H Chang, H de Silva, H Heyn, X Deng, RK Egan… - Cell, 2016 - cell.com
Systematic studies of cancer genomes have provided unprecedented insights into the
molecular nature of cancer. Using this information to guide the development and application of …
molecular nature of cancer. Using this information to guide the development and application of …
[HTML][HTML] MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies
We previously reported on MetaBAT, an automated metagenome binning software tool to
reconstruct single genomes from microbial communities for subsequent analyses of …
reconstruct single genomes from microbial communities for subsequent analyses of …
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish
The zebrafish (Danio rerio) is emerging as a promising model organism for experimental
studies of stress and anxiety. Here we further validate zebrafish models of stress by analyzing …
studies of stress and anxiety. Here we further validate zebrafish models of stress by analyzing …
[HTML][HTML] MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities
… | T P T P D | T + P R P D | R where T or R represent cases where two contigs are from … R
were chosen. In reality, P(T) is expected to be much bigger than P(R), thus we set P(T) = 10∗P(R…
were chosen. In reality, P(T) is expected to be much bigger than P(R), thus we set P(T) = 10∗P(R…
[HTML][HTML] Interleukin (IL)-10 inhibits nuclear factor кB (NFкB) activation in human monocytes: IL-10 and IL-4 suppress cytokine synthesis by different mechanisms (∗)
P Wang, P Wu, MI Siegel, RW Egan… - Journal of Biological …, 1995 - ASBMB
Our previous studies in human monocytes have demonstrated that interleukin (IL)-10 inhibits
lipopolysaccharide (LPS)-stimulated production of inflammatory cytokines, IL-1β, IL-6, IL-8, …
lipopolysaccharide (LPS)-stimulated production of inflammatory cytokines, IL-1β, IL-6, IL-8, …