User profiles for R. Eils
 | Roland EilsProfessor for Digital Health, Charité-Universitätsmedizin Berlin and Berlin Institute of Health Verified email at charite.de Cited by 76665 |
Signatures of mutational processes in human cancer
All cancers are caused by somatic mutations; however, understanding of the biological
processes generating these mutations is limited. The catalogue of somatic mutations from a …
processes generating these mutations is limited. The catalogue of somatic mutations from a …
[HTML][HTML] Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
The newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events throughout …
COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events throughout …
Computational imaging in cell biology
Microscopy of cells has changed dramatically since its early days in the mid-seventeenth
century. Image analysis has concurrently evolved from measurements of hand drawings and …
century. Image analysis has concurrently evolved from measurements of hand drawings and …
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
… In the R programming environment, traditional tools for drawing heatmaps, … Data sources
and R code for the plots can be found at … Data sources and R code for the plots can be found at …
and R code for the plots can be found at … Data sources and R code for the plots can be found at …
[HTML][HTML] COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
The human cell atlas
10.7554/eLife.27041.001 The recent advent of methods for high-throughput single-cell
molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe …
molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe …
SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
… a trend for increasing overall expression of ACE2 with age for all female lung samples (R
2 … Statistical analyses were performed using R and Python 3.7.1 with scipy 0.14.1 and …
2 … Statistical analyses were performed using R and Python 3.7.1 with scipy 0.14.1 and …
[HTML][HTML] The landscape of genomic alterations across childhood cancers
Pan-cancer analyses that examine commonalities and differences among various cancer
types have emerged as a powerful way to obtain novel insights into cancer biology. Here we …
types have emerged as a powerful way to obtain novel insights into cancer biology. Here we …
[HTML][HTML] Dissecting the genomic complexity underlying medulloblastoma
…, C von Kalle, V Ast, C Lawerenz, J Eils, R Kabbe… - Nature, 2012 - nature.com
Medulloblastoma is an aggressively growing tumour, arising in the cerebellum or medulla/brain
stem. It is the most common malignant brain tumour in children, and shows tremendous …
stem. It is the most common malignant brain tumour in children, and shows tremendous …
[HTML][HTML] The whole-genome landscape of medulloblastoma subtypes
… The genome was segmented using the PSCBS package in R 49 while incorporating
structural variant breakpoints defined by DELLY. Segments were clustered using k-means …
structural variant breakpoints defined by DELLY. Segments were clustered using k-means …