We characterized metabolic and mitogenic signaling pathways in isolated skeletal muscle
from well-matched type 2 diabetic and control subjects. Time course studies of the insulin …

Recent advances in DNA-sequencing technology have made it possible to obtain large datasets
of small RNA sequences. Here we demonstrate that not all non-perfectly matched small …

Target identification is an essential part of the drug discovery and development process, and
its efficacy plays a crucial role in the success of any given therapy. Although protein target …

Growing evidence suggests that activation of mitogen-activated protein kinase (MAPK)
signal transduction mediates changes in muscle gene expression in response to exercise. …

Protein degradation is a crucial regulatory process in maintaining cellular proteostasis. The
selective degradation of intracellular proteins controls diverse cellular and biochemical …

MicroRNAs (miRNAs) are genome-encoded small double-stranded RNAs that have
emerged as key regulators of gene expression and are implicated in most aspects of human …

… Fahlman … The Fahlman lab research is supported by the Canadian Cancer Society (Grant
#: 704722). … We would like to thank all the Fahlman lab members. …

MicroRNAs (miRNAs) regulate gene expression in a variety of biological pathways such as
development and tumourigenesis. miRNAs are initially expressed as long primary transcripts …

To determine the role of GLUT4 on postexercise glucose transport and glycogen resynthesis
in skeletal muscle, GLUT4‐deficient and wild‐type mice were studied aftera3h swim …

… Val, and Glu-tRNAGlu were found to be identical to those of determining KD (Fahlman
and … in tRNA on codon was performed essentially as previously described (Fahlman and …