This study tested the claim that digital PCR (dPCR) can offer highly reproducible quantitative
measurements in disparate laboratories. Twenty-one laboratories measured four blinded …

… Baekelandt M, Kristensen GB, Trope CG, Nesland JM and Holm R: Epidermal growth factor
receptor expression has no independent prognostic significance in advanced ovarian cancer…

This commentary attempts to discuss the required standardization of circulating tumor DNA
(ctDNA) analyses and thereby improve the clinical validity of ctDNA monitoring in the …

Background Circulating cell-free DNA (cfDNA) in plasma has shown potential as biomarker
in various cancers and could become an importance source for tumour mutation detection. …

BACKGROUND: Lung cancer is one of the most common malignant diseases worldwide and
associated with considerable morbidity and mortality. New agents targeting the epidermal …

KRAS and BRAF mutations are responsible for primary resistance to epidermal growth factor
receptor (EGFR) MoAbs in metastatic colorectal cancer (mCRC), but it is unknown what …

Numerous studies have reported a potential role for circulating microRNAs as biomarkers in
a wide variety of diseases. However, there is a critical reproducibility challenge some of …

Recent research has focused on the utility of cell free DNA (cfDNA) in serum and plasma for
clinical application, especially in oncology. The literature holds promise of cfDNA as a …

Delta tocotrienol has anti-neoplastic activity as demonstrated in several in-vitro and in-vivo
investigations. The effect relies on inhibition of different pathways. It also has antiangiogenic …

… Author links open overlay panel Karen-Lise Garm Spindler a c , Niels Pallisgaard b , Ane
Lindegaard Appelt c , Rikke Fredslund Andersen b , Jakob V. Schou d , Dorte Nielsen d g , Per …