User profiles for R. Hoendorf
Robert HoehndorfKing Abdullah University of Science and Technology Verified email at kaust.edu.sa Cited by 7480 |
Text-mining solutions for biomedical research: enabling integrative biology
…, A Oellrich, R Hoehndorf - Nature Reviews …, 2012 - nature.com
In response to the unbridled growth of information in literature and biomedical databases,
researchers require efficient means of handling and extracting information. As well as …
researchers require efficient means of handling and extracting information. As well as …
Semantic similarity and machine learning with ontologies
Ontologies have long been employed in the life sciences to formally represent and reason
over domain knowledge and they are employed in almost every major biological database. …
over domain knowledge and they are employed in almost every major biological database. …
[HTML][HTML] The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
…, WH Liao, YW Liu, S Pascarelli, Y Frank, R Hoehndorf… - Genome biology, 2019 - Springer
Background The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global,
community-driven effort to evaluate and improve the computational annotation of protein …
community-driven effort to evaluate and improve the computational annotation of protein …
DeepGO: predicting protein functions from sequence and interactions using a deep ontology-aware classifier
Motivation A large number of protein sequences are becoming available through the
application of novel high-throughput sequencing technologies. Experimental functional …
application of novel high-throughput sequencing technologies. Experimental functional …
Mouse genetic and phenotypic resources for human genetics
PN Schofield, R Hoehndorf, GV Gkoutos - Human mutation, 2012 - Wiley Online Library
The use of model organisms to provide information on gene function has proved to be a
powerful approach to our understanding of both human disease and fundamental mammalian …
powerful approach to our understanding of both human disease and fundamental mammalian …
DeepGOPlus: improved protein function prediction from sequence
M Kulmanov, R Hoehndorf - Bioinformatics, 2020 - academic.oup.com
… Maxat Kulmanov, Robert Hoehndorf, DeepGOPlus: improved protein function prediction
from … per second using a single Intel(R) Xeon(R) E5-2680 CPU and Nvidia P6000 GPU. …
from … per second using a single Intel(R) Xeon(R) E5-2680 CPU and Nvidia P6000 GPU. …
The role of ontologies in biological and biomedical research: a functional perspective
R Hoehndorf, PN Schofield… - Briefings in …, 2015 - academic.oup.com
Ontologies are widely used in biological and biomedical research. Their success lies in their
combination of four main features present in almost all ontologies: provision of standard …
combination of four main features present in almost all ontologies: provision of standard …
[HTML][HTML] The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery
…, MD Wilkinson, R Hoehndorf - Journal of biomedical …, 2014 - Springer
The Semanticscience Integrated Ontology (SIO) is an ontology to facilitate biomedical knowledge
discovery. SIO features a simple upper level comprised of essential types and relations …
discovery. SIO features a simple upper level comprised of essential types and relations …
[HTML][HTML] FoodOn: a harmonized food ontology to increase global food traceability, quality control and data integration
The construction of high capacity data sharing networks to support increasing government
and commercial data exchange has highlighted a key roadblock: the content of existing …
and commercial data exchange has highlighted a key roadblock: the content of existing …
PhenomeNET: a whole-phenome approach to disease gene discovery
R Hoehndorf, PN Schofield… - Nucleic acids research, 2011 - academic.oup.com
… , where P is characterized by the ontology classes Cl(P) = P 1 ,...,P n and R is
characterized by the classes Cl(R) = R 1 ,...,R m , we define the similarity between P and R as: …
characterized by the classes Cl(R) = R 1 ,...,R m , we define the similarity between P and R as: …