Dopamine genes and attention-deficit hyperactivity disorder: a review

S DiMaio, N Grizenko, R Joober - Journal of Psychiatry and Neuroscience, 2003 - jpn.ca
… ADHD diagnosis in subjects with Tourette’s syndrome and genetic loading for specific alleles
of DRD2, SLC6A3 and DBH genes (in order of relative importance based on correlation [r

From early intervention in psychosis to youth mental health reform: a review of the evolution and transformation of mental health services for young people

…, H Coughlan, S Singh, P Jones, R Joober - Social psychiatry and …, 2016 - Springer
Purpose The objective of this review is to report on recent developments in youth mental
health incorporating all levels of severity of mental disorders encouraged by progress in the …

First-episode psychosis, early intervention, and outcome: what have we learned?

…, RMG Norman, R Joober - The Canadian Journal of …, 2005 - journals.sagepub.com
Objective: There has been increased interest in the potential of early intervention to positively
influence outcome in first-episode psychosis (FEP) and, consequently, to influence mental …

LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia

…, N Matsumoto-Itaba, J Nicod, L Xiong, R Joober… - Molecular …, 2007 - nature.com
Left–right asymmetrical brain function underlies much of human cognition, behavior and
emotion. Abnormalities of cerebral asymmetry are associated with schizophrenia and other …

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

…, LE DeLisi, MO Krebs, R Joober… - Proceedings of the …, 2010 - National Acad Sciences
Schizophrenia likely results from poorly understood genetic and environmental factors. We
studied the gene encoding the synaptic protein SHANK3 in 285 controls and 185 …

Novel de novo SHANK3 mutation in autistic patients

…, L Mottron, É Fombonne, R Joober… - American Journal of …, 2009 - Wiley Online Library
A number of studies have confirmed that genetic factors play an important role in autism
spectrum disorder (ASD). More recently de novo mutations in the SHANK3 gene, a synaptic …

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

…, A Addington, LE Delisi, L Mottron, R Joober… - Molecular …, 2011 - nature.com
Autism spectrum disorder (ASD) and schizophrenia (SCZ) are two common neurodevelopmental
syndromes that result from the combined effects of environmental and genetic factors. …

[HTML][HTML] Mutations in SYNGAP1 in Autosomal Nonsyndromic Mental Retardation

…, MO Krebs, F Mouaffak, R Joober… - … England Journal of …, 2009 - Mass Medical Soc
<p id="p001">Although autosomal forms of nonsyndromic mental retardation account for the
majority of cases of mental retardation, the genes that are involved remain largely unknown. …

Increased exonic de novo mutation rate in individuals with schizophrenia

…, AHY Tong, CH Lin, B Millet, N Jaafari, R Joober… - Nature …, 2011 - nature.com
Schizophrenia is a severe psychiatric disorder that profoundly affects cognitive, behavioral
and emotional processes. The wide spectrum of symptoms and clinical variability in …

Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit …

…, C Vanier, M Alda, R Joober… - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Postmortem studies have indicated that suicide victims have greater serotonin
receptor 2A (5-HTR 2A ) binding in prefrontal brain regions. However, there remains some …