Bone reconstruction techniques are mainly based on the use of tissue grafts and artificial
scaffolds. The former presents well-known limitations, such as restricted graft availability and …

Effective treatment of chronic lower limb ischemia is one of the most challenging issues
confronting vascular surgeons. There are a number of choices available to the vascular surgeon. …

Bone grafts are medical devices that are in high demand in clinical practice for substitution
of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern …

Bioceramics are used to treat bone defects but in general do not induce formation of new
bone, which is essential for regeneration process. Many aspects related to bioceramics …

Biocompatible calcium phosphate ceramic grafts are able of supporting new bone formation
in appropriate environment. The major limitation of these materials usage for medical …

The aim of the study was the development of three-dimensional (3D) printed gene-activated
implants based on octacalcium phosphate (OCP) and plasmid DNA encoding VEGFA. The …

Treatment of patients with large bone defects is a complex clinical problem. We have
initiated the first clinical study of a gene-activated bone substitute composed of the collagen-…

Bone grafting and reconstruction are still challenging in clinical practice because of the
limitations of bone autografts and the drawbacks of currently approved bone substitutes. We thus …

Artificial tissue‐engineered grafts offer a potential alternative to autologous tissue grafts for
patients, which can be traumatic. After decellularizing Papio hamadryas esophagus and …

The widespread use of magnetic resonance imaging (MRI) in the diagnosis of myopathies
has made it possible to clarify the typical MRI pattern of dysferlinopathy. However, sufficient …