Energy homeostasis is controlled by a complex neuroendocrine system consisting of
peripheral signals like leptin and central signals, in particular, neuropeptides. Several …

Mutations in the human melanocortin (MC)4 receptor have been associated with obesity,
which underscores the relevance of this receptor as a drug target to treat obesity. Infusion of …

Does it matter what we eat for our mental health? Accumulating data suggests that this may
indeed be the case and that diet and nutrition are not only critical for human physiology and …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

… Roger AH Adan Roger AH Adan … RA H Adan, Rudolf Magnus Institute for
Neurosciences, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands. …

Health nudge interventions to steer people into healthier lifestyles are increasingly applied
by governments worldwide, and it is natural to look to such approaches to improve health by …

Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

The consumption of W estern diets, high in sugar and saturated fat, is a crucial contributor to
the alarming incidence of obesity and its associated morbidities. These diets have been …

Surface metallization by plasma coating enhances desorption/ionization of membrane
components such as lipids and sterols in imaging time-of-flight secondary ion mass spectrometry (…

Background: New genetic loci, most of which are expressed in the brain, have recently been
reported to contribute to the development of obesity. The brain, especially the hypothalamus…