User profiles for Rachael Ivison

Rachael Ivison

Data Management Specialist, Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Cited by 51

PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity

…, T Belchior, P Chimin, J Magdalon, R Ivison… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The nutrient sensors peroxisome proliferator-activated receptor γ (PPARγ) and mechanistic
target of rapamycin complex 1 (mTORC1) closely interact in the regulation of adipocyte lipid …

Grid-based temporal logic inference

P Vaidyanathan, R Ivison, G Bombara… - 2017 IEEE 56th …, 2017 - ieeexplore.ieee.org
This paper introduces a new algorithm to infer temporal logic properties of a system from
data consisting of a set of finite time system traces. We propose an algorithm that generates a …

[HTML][HTML] HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

…, SA Hannou, W Tong, H Srinivasan, R Ivison… - JCI insight, 2023 - ncbi.nlm.nih.gov
Carbohydrate response element–binding protein (ChREBP) is a carbohydrate-sensing
transcription factor that regulates both adaptive and maladaptive genomic responses in …

Integrated genomic analysis of AgRP neurons reveals that IRF3 regulates leptin's hunger-suppressing effects

FD Heyward, N Liu, C Jacobs, R Ivison, N Machado… - bioRxiv, 2022 - biorxiv.org
AgRP neurons in the arcuate nucleus of the hypothalamus (ARC) coordinate homeostatic
changes in appetite associated with fluctuations in food availability and leptin signaling. …

HGFAC is a ChREBP regulated hepatokine that enhances glucose and lipid homeostasis

…, L Doridot, SA Hannou, W Tong, H Srinivasan, R Ivison… - bioRxiv, 2021 - biorxiv.org
Carbohydrate Responsive Element-Binding Protein (ChREBP) is a carbohydrate sensing
transcription factor that regulates both adaptive and maladaptive genomic responses in …

Semi-supervised pattern synthesis in spatially distributed dynamical systems

I Haghighi, K Leahy, R Ivison… - 2017 American Control …, 2017 - ieeexplore.ieee.org
Pattern producing networks of dynamical systems are useful in a variety of applications
ranging from formation control in multi-agent robotics to biological networks. We propose a …

Truck versus human: mathematics under pressure

E Field, R Ivison, A Reyher, S Warner - The College Mathematics …, 2014 - Taylor & Francis
If you are ever faced with an oncoming truck, this paper could save your life. We investigate
the optimal path that you should take from the middle of the road to the curb in order to avoid …

[PDF][PDF] Utilizing Signal Temporal Logic to Characterize and Compose Modules in Synthetic Biology

C Madsen, P Vaidyanathan, CI Vasile, R Ivison… - cristianvasile.com
The goal of synthetic biology is to allow biologists and engineers to design and build new
biological systems. One way this task is achieved is though the composition of DNA segments …

2293-PUB: Epigenomic Analysis of AgRP Neurons Reveals That Leptin Induces Satiety via IRF3

FD Heyward, R Ivison, LTY Tsai, E Rosen - Diabetes, 2020 - Am Diabetes Assoc
AgRP neurons in the arcuate nucleus (ARC) of the hypothalamus play a dominant role in
maintaining energy balance and are dysregulated in obesity, but prior studies examining their …

582-P: Disambiguating the Nucleus Ambiguous with Single-Cell Transcriptomics

T Coverdell, R Ivison, J Tao, J Campbell - Diabetes, 2019 - Am Diabetes Assoc
The nucleus ambiguous (nAmb), a hindbrain region which degenerates in diabetes models,
is the major parasympathetic input to the heart but also innervates the larynx and …