Background Artificial gut models provide unique opportunities to study human-associated
microbiota. Outstanding questions for these models’ fundamental biology include the …

PCR amplification plays an integral role in the measurement of mixed microbial communities
via high-throughput DNA sequencing of the 16S ribosomal RNA (rRNA) gene. Yet PCR is …

Culture and screening of gut bacteria enable testing of microbial function and therapeutic
potential. However, the diversity of human gut microbial communities (microbiota) impedes …

Bipolar disorder (BIP) is a highly heritable disorder with complex patterns of genetic inheritance,
and recent genetic findings highlight the role of numerous common variants each with …

Isolation and culture of gut bacteria enable testing for microbial roles in disease and may
also lead to novel therapeutics. However, the diversity of human gut microbial communities (…

Copy number variation plays a clear role in the etiology of many psychiatric disorders,
particularly schizophrenia. We performed array-CGH to look for copy number variants between …

PCR amplification plays a central role in the measurement of mixed microbial communities
via high-throughput sequencing. Yet PCR is also known to be a common source of bias in …

We applied multiple complementary genomic technologies to this pedigree including SNP
genotyping using the Illumina OMNI 1M chip, high density copy number variant mapping …

The hundreds of microbes that inhabit the human gut play a large role in human health and
disease. The ability to isolate and culture bacteria from within the human gut allows us to …

More than 80% of college students switch degree programs, and students in selective majors,
such as business and nursing, often face complex processes with serious implications …