Establishment and evolution of the A ustralian I nherited R etinal D isease R egister and DNA B ank
…, RL Paterson, EC O'Brien, L Hoffmann… - Clinical & …, 2013 - Wiley Online Library
Background Inherited retinal disease represents a significant cause of blindness and visual
morbidity worldwide. With the development of emerging molecular technologies, accessible …
morbidity worldwide. With the development of emerging molecular technologies, accessible …
Structure‐guided stabilization of pathogen‐derived peptide‐HLA‐E complexes using non‐natural amino acids conserves native TCR recognition
C Barber, VA De Souza, RL Paterson… - European Journal of …, 2022 - Wiley Online Library
The nonpolymorphic class Ib molecule, HLA‐E, primarily presents peptides from HLA class
Ia leader peptides, providing an inhibitory signal to NK cells via CD94/NKG2 interactions. …
Ia leader peptides, providing an inhibitory signal to NK cells via CD94/NKG2 interactions. …
Generation of Monocyte-Derived Dendritic Cells with Differing Sialylated Phenotypes
Sialic acids are negatively charged monosaccharides typically found at the termini of cell
surface glycans. Due to their hydrophilicity and biophysical characteristics, they are involved in …
surface glycans. Due to their hydrophilicity and biophysical characteristics, they are involved in …
[HTML][HTML] Instability of the HLA-E peptidome of HIV presents a major barrier to therapeutic targeting
Z Wallace, T Heunis, RL Paterson, RJ Suckling… - Molecular Therapy, 2024 - cell.com
Naturally occurring T cells that recognize microbial peptides via HLA-E, a nonpolymorphic
HLA class Ib molecule, could provide the foundation for new universal immunotherapeutics. …
HLA class Ib molecule, could provide the foundation for new universal immunotherapeutics. …
[HTML][HTML] A generic cell surface ligand system for studying cell–cell recognition
…, SM Black, MJ Bridge, B de Wet, RL Paterson… - PLoS …, 2019 - journals.plos.org
Dose-response experiments are a mainstay of receptor biology studies and can reveal
valuable insights into receptor function. Such studies of receptors that bind cell surface ligands …
valuable insights into receptor function. Such studies of receptors that bind cell surface ligands …
Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface
Sialic acids are negatively charged monosaccharides typically found at the termini of cell
surface glycans. Due to their hydrophilicity and biophysical characteristics, they are involved in …
surface glycans. Due to their hydrophilicity and biophysical characteristics, they are involved in …
[HTML][HTML] Application of a high-throughput genotyping method for loci exclusion in non-consanguineous Australian pedigrees with autosomal recessive retinitis …
RL Paterson, JN De Roach, TL McLaren… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose Retinitis pigmentosa (RP) is the most common form of inherited blindness, caused
by progressive degeneration of photoreceptor cells in the retina, and affects approximately 1 …
by progressive degeneration of photoreceptor cells in the retina, and affects approximately 1 …
Ligand requirements for immunoreceptor triggering
Leukocytes interact physically with other cells using cell surface receptors. The largest group
of such receptors are non-catalytic tyrosine phosphorylated receptors (NTRs), also called …
of such receptors are non-catalytic tyrosine phosphorylated receptors (NTRs), also called …
The Combination of Colistin and Doripenem Is Synergistic against Klebsiella pneumoniae at Multiple Inocula and Suppresses Colistin Resistance in an In Vitro …
…, JB Bulitta, A Forrest, DL Paterson… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Multidrug-resistant (MDR) Klebsiella pneumoniae may require combination therapy. We
systematically investigated bacterial killing with colistin and doripenem mono- and combination …
systematically investigated bacterial killing with colistin and doripenem mono- and combination …
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
RW Paterson, RL Brown, L Benjamin, R Nortley… - Brain, 2020 - academic.oup.com
Preliminary clinical data indicate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection is associated with neurological and neuropsychiatric illness. Responding …
infection is associated with neurological and neuropsychiatric illness. Responding …