Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

…, S Zumhagen, ER Behr, R Bastiaenen… - Nature …, 2013 - nature.com
Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A
mutations in around 20% of cases 1 , 2 , 3 . Through a genome-wide association study of 312 …

Clinical usefulness, angiographic characteristics, and safety evaluation of intracoronary acetylcholine provocation testing among 921 consecutive white patients with …

…, A Athanasiadis, G Borgulya, I Vokshi, R Bastiaenen… - Circulation, 2014 - Am Heart Assoc
Background— Coronary spasm can cause myocardial ischemia and angina in patients with
and those without obstructive coronary artery disease. However, provocation tests using …

Sudden cardiac death in young athletes: practical challenges and diagnostic dilemmas

N Chandra, R Bastiaenen, M Papadakis… - Journal of the American …, 2013 - jacc.org
Sudden cardiac death (SCD) in an athlete is a rare yet highly visible tragedy that generates
significant media attention and discussion among medical personnel, sports communities, …

Common Variation in the NOS1AP Gene Is Associated With Drug-Induced QT Prolongation and Ventricular Arrhythmia

…, D Zheng, T Johnson, R Bastiaenen… - Journal of the American …, 2012 - jacc.org
Objectives : This study sought to determine whether variations in NOS1AP affect drug-induced
long QT syndrome (LQTS). Background : Use of antiarrhythmic drugs is limited by the high …

Anterior T-wave inversion in young white athletes and nonathletes: prevalence and significance

…, S Gati, TJ Yeo, H Dores, R Bastiaenen… - Journal of the American …, 2017 - jacc.org
Background : Anterior T-wave inversion (ATWI) on electrocardiography (ECG) in young white
adults raises the possibility of cardiomyopathy, specifically arrhythmogenic right ventricular …

The diagnostic yield of Brugada syndrome after sudden death with normal autopsy

…, G Mellor, H Raju, R Bastiaenen… - Journal of the American …, 2018 - jacc.org
Background : Familial evaluation after a sudden death with negative autopsy (sudden
arrhythmic death syndrome; SADS) may identify relatives at risk of fatal arrhythmias. Objectives : …

Clinical significance of electrocardiographic right ventricular hypertrophy in athletes: comparison with arrhythmogenic right ventricular cardiomyopathy and pulmonary …

…, S Ghani, N Sheikh, S Gati, R Bastiaenen… - European heart …, 2013 - academic.oup.com
Aims Pre-participation cardiovascular screening of young athletes may prevent sports-related
sudden cardiac deaths. Recognition of physiological electrocardiography (ECG) changes …

Prevalence of electrocardiographic anomalies in young individuals: relevance to a nationwide cardiac screening program

N Chandra, R Bastiaenen, M Papadakis… - Journal of the American …, 2014 - jacc.org
Objectives : This study sought to investigate the prevalence of potentially abnormal
electrocardiographic (ECG) patterns in young individuals to assess the implications for a nationwide …

Low prevalence of risk markers in cases of sudden death due to Brugada syndrome: relevance to risk stratification in Brugada syndrome

…, M Papadakis, M Govindan, R Bastiaenen… - Journal of the American …, 2011 - jacc.org
Objectives : The objective of this study was to determine the prevalence of conventional risk
factors in sudden arrhythmic death syndrome (SADS) probands with Brugada syndrome (BrS…

Electrocardiographic differentiation between 'benign T-wave inversion'and arrhythmogenic right ventricular cardiomyopathy

…, B Ensam, CJ Miles, R Bastiaenen… - Ep …, 2019 - academic.oup.com
Aims To characterize the most common electrocardiographic (ECG) abnormalities in
patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), including anterior T-wave …