User profiles for Rachel C. Williams

Rachel C. Williams

Bangor University
Verified email at bangor.ac.uk
Cited by 229

Cryptic patterns of speciation in cryptic primates: microendemic mouse lemurs and the multispecies coalescent

…, AR Stahlke, DW Weisrock, RC Williams… - Systematic …, 2021 - academic.oup.com
Mouse lemurs (Microcebus) are a radiation of morphologically cryptic primates distributed
throughout Madagascar for which the number of recognized species has exploded in the past …

[HTML][HTML] Production of Bacillus anthracis protective antigen is dependent on the extracellular chaperone, PrsA

RC Williams, ML Rees, MF Jacobs, Z Prágai… - Journal of Biological …, 2003 - ASBMB
Protective antigen (PA) is a component of theBacillus anthracis lethal and edema toxins and
the basis of the current anthrax vaccine. In its heptameric form, PA targets host cells and …

[HTML][HTML] Next-generation technologies applied to age-old challenges in Madagascar

…, F Rasambainarivo, E Toomey, RC Williams… - Conservation …, 2020 - Springer
Madagascar is a biodiversity hotspot that is facing rapid rates of deforestation, habitat destruction,
and poverty. Urgent action is required to document the status of biodiversity to facilitate …

[HTML][HTML] Leptin and pro-inflammatory stimuli synergistically upregulate MMP-1 and MMP-3 secretion in human gingival fibroblasts

RC Williams, AJ Skelton, SM Todryk, AD Rowan… - PloS one, 2016 - journals.plos.org
Introduction Gingival fibroblast-mediated extracellular matrix remodelling is implicated in
the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully …

The extracellular and cytoplasmic proteomes of the non‐virulent Bacillus anthracis strain UM23C1‐2

H Antelmann, RC Williams, M Miethke, A Wipat… - …, 2005 - Wiley Online Library
The recently published genome sequence of Bacillus anthracis Ames has facilitated the
prediction of proteins associated with the virulence of this bacterium. The aim of this study was to …

Neutral theory is the foundation of conservation genetics

…, JW Poelstra, GP Tiley, RC Williams - Molecular Biology and …, 2018 - academic.oup.com
Kimura’s neutral theory of molecular evolution has been essential to virtually every advance
in evolutionary genetics, and by extension, is foundational to the field of conservation …

[HTML][HTML] Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar's hibernating dwarf lemurs

RC Williams, MB Blanco, JW Poelstra, KE Hunnicutt… - Heredity, 2020 - nature.com
Madagascar’s biodiversity is notoriously threatened by deforestation and climate change.
Many of these organisms are rare, cryptic, and severely threatened, making population-level …

Simultaneous detection and characterization of common respiratory pathogens in wastewater through genomic sequencing

RC Williams, A Garcia-Delgado, L Adwan, JL Kevill… - Water Research, 2024 - Elsevier
Genomic surveillance of SARS-CoV-2 has given insight into the evolution and epidemiology
of the virus and its variant lineages during the COVID-19 pandemic. Expanding this …

Comparative assessment of Nanotrap and polyethylene glycol-based virus concentration in wastewater samples

K Farkas, JL Kevill, RC Williams, I Pântea… - FEMS …, 2024 - academic.oup.com
Wastewater-based epidemiology is now widely used in many countries for the routine
monitoring of SARS-CoV-2 and other viruses at a community level. However, efficient sample …

Next-generation in situ conservation and educational outreach in Madagascar using a mobile genetics lab

MB Blanco, LK Greene, RC Williams… - BioRxiv, 2019 - biorxiv.org
Madagascar is a biodiversity hotspot that is facing rapid rates of deforestation, habitat destruction
and poverty. Urgent action is required to document the status of biodiversity to facilitate …