Tractable microbial communities are needed to bridge the gap between observations of
patterns of microbial diversity and mechanisms that can explain these patterns. We developed …

Long-term dietary intake influences the structure and activity of the trillions of microorganisms
residing in the human gut 1 , 2 , 3 , 4 , 5 , but it remains unclear how rapidly and …

Microbial communities of fermented foods have provided humans with tools for preservation
and flavor development for thousands of years. These simple, reproducible, accessible, …

The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

The vast majority of bacteria, including human pathogens and microbiome species, lack
genetic tools needed to systematically associate genes with phenotypes. This is the major …

Genomics and metabolomics are widely used to explore specialized metabolite diversity.
The Paired Omics Data Platform is a community initiative to systematically document links …

Protein disulfide bond formation contributes to the folding and activity of many exported
proteins in bacteria. However, information about disulfide bond formation is limited to only a few …

Vitamin K epoxide reductase (VKOR) generates vitamin K hydroquinone to sustain γ-carboxylation
of many blood coagulation factors. Here, we report the 3.6 Å crystal structure of a …

We engineered a machine learning approach, MSHub, to enable auto-deconvolution of gas
chromatography–mass spectrometry (GC–MS) data. We then designed workflows to enable …

… Author links open overlay panel Emily C Pierce 1 , Rachel J Dutton 1 2 … Pogliano, BE
Wolfe, LM Sanchez, RJ Dutton … Morin, EC Pierce, RJ Dutton …