Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …

Areas of concern (AOCs) around the Great Lakes are characterized by historic and ongoing
problems with microbial water quality, leading to beneficial use impairments (BUIs) such as …

Identification of sources of fecal pollution in urban areas is critical for protecting public health,
the environment, and guiding remediation. We collected 670 water samples at 46 sites in …

Parasite-mediated selection is widespread at loci involved in immune defense, but different
defenses may experience different selective regimes. For defenses involved in clearing …

Simple Summary Ring chromosomes (RCs) are formed when chromosome ends fuse to
form a circular structure. RCs are seen in <10% of patients with blood cancers (ie, leukemias, …

Recent collaborative genome wide association studies (GWAS) have identified >200
independent loci contributing to risk for schizophrenia (SCZ). The genes closest to these loci have …

To overcome the ethical and technical limitations of in vivo human disease models, the broader
scientific community frequently employs model organism-derived cell lines to investigate …

Cells with loss of BRCA2 function are defective in homologous recombination (HR) and are
highly sensitive to inhibitors of poly(ADP-ribose) polymerase (PARP) 1 , 2 , which provides …

Objective To study the relationship between soft tissue volume loss and bone resection length
following lateral segmental mandibulectomy with plate reconstruction and complication …

An experiment was conducted to examine factors that moderate the experience of academic
identity threat among college athletes who represent a stigmatized group on most college …