Reactive oxidant species (superoxide, hydrogen peroxide, hydroxyl radical, hypohalous
acid, and nitric oxide) are involved in many of the complex interactions between the invading …

Background Anaphylaxis is a severe, life-threatening allergic reaction that affects both children
and adults in the United States. However, data regarding the incidence and prevalence …

Background Clinical treatment goals of type 1 diabetes mellitus (T1DM) have changed
since the Diabetes Control and Complications Trial (DCCT) demonstrated reduced long-term …

OBJECTIVE: To improve understanding of the epidemiology of anaphylaxis. DATA
SOURCES: We performed a qualitative review by hand of the major epidemiology studies of …

Diabetes is a major risk factor for atherosclerosis. Although atherosclerosis is initiated by
deposition of cholesterol-rich lipoproteins in the artery wall, the entry of inflammatory leukocytes …

Like many microalgae, Chlamydomonas reinhardtii forms lipid droplets rich in triacylglycerols
when nutrient deprived. To begin studying the mechanisms underlying this process, …

Bisphenol A (BPA) is an estrogenic endocrine disruptor widely used in the production of
plastics. Increasing evidence indicates that in utero BPA exposure affects sexual differentiation …

In a longitudinal cohort of ∼700 children in New York City, the prevalence of asthma (>25%)
is among the highest in the US. This high risk may in part be caused by transplacental …

Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Recent studies suggest that epigenetic regulation (heritable changes in gene expression
that occur in the absence of alterations in DNA sequences) may in part mediate the complex …