The functional role of heteromers of G-protein-coupled receptors is a matter of debate. In the
present study, we demonstrate that heteromerization of adenosine A 1 receptors (A 1 Rs) …

Antagonistic and reciprocal interactions are known to exist between adenosine and dopamine
receptors in the striatum. In the present study, double immunofluorescence experiments …

The possible molecular basis for the previously described antagonistic interactions between
adenosine A 1 receptors (A 1 R) and dopamine D 1 receptors (D 1 R) in the brain have …

Receptor heteromers constitute a new area of research that is reshaping our thinking about
biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we …

During the last 10 years, adenosine deaminase (ADA), an enzyme considered to be
cytosolic, has been found on the cell surface of many cells, therefore it can be considered an …

Despite some caveats, G protein-coupled receptor oligomerization is a phenomenon that is
becoming largely accepted. Within these oligomers, however, stoichiometry remains to be …

Macrophages are important players in the fight against viral, bacterial, fungal and parasitic
infections. From a resting state they may undertake two activation pathways, the classical …

There is evidence for strong functional antagonistic interactions between adenosine A 2A
receptors (A 2A Rs) and dopamine D 2 receptors (D 2 Rs). Although a close physical …

The physiological meaning of the coexpression of adenosine A2A receptors and group I
metabotropic glutamate receptors in γ- aminobutyric acid (GABA)ergic striatal neurons is …

G protein‐coupled receptors are known to form homo‐ and heteromers at the plasma
membrane, but the stoichiometry of these receptor oligomers are relatively unknown. Here, by …