User profiles for Rafael Henrique Nóbrega

Rafael Henrique Nobrega

Professor Assistente, Biologia Celular, Histo, Embrio, UNESP-Botucatu
Verified email at ibb.unesp.br
Cited by 4016

Spermatogenesis in fish

…, F LeGac, H Chiarini-Garcia, RH Nobrega… - General and …, 2010 - Elsevier
Spermatogenesis is a developmental process during which a small number of diploid
spermatogonial stem cells produce a large number of highly differentiated spermatozoa carrying a …

[HTML][HTML] Spermatogonial stem cell niche and spermatogonial stem cell transplantation in zebrafish

RH Nobrega, CD Greebe, H van de Kant, J Bogerd… - PloS one, 2010 - journals.plos.org
Background Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and
reside within a specific microenvironment in the testes called “niche” which regulates stem …

Fsh stimulates spermatogonial proliferation and differentiation in zebrafish via Igf3

RH Nóbrega, RDVS Morais, D Crespo… - …, 2015 - academic.oup.com
Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We
investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a steroid…

Gastroprotective effect of limonene in rats: Influence on oxidative stress, inflammation and gene expression

…, AJ Vieira, FP Beserra, CH Pellizzon, RH Nóbrega… - Phytomedicine, 2019 - Elsevier
Background In an increasing search for natural products that may heal the ulcers and avoid
its recurrence, limonene appears as a promising candidate. Hypothesis/Purpose The …

Multiple endpoints of polylactic acid biomicroplastic toxicity in adult zebrafish (Danio rerio)

TQ Chagas, IN Freitas, MF Montalvão, RH Nobrega… - Chemosphere, 2021 - Elsevier
Although the toxicity of conventional microplastic types (ie, petroleum derivatives) in different
organisms is already known, knowledge about the effects of alternative biopolymers on …

[HTML][HTML] Lupeol, a dietary triterpene, enhances wound healing in streptozotocin-induced hyperglycemic rats with modulatory effects on inflammation, oxidative stress …

…, MF Hussni, CA Hussni, RH Nóbrega… - … medicine and cellular …, 2019 - hindawi.com
Impaired wound healing is a debilitating complication of diabetes that leads to significant
morbidity, particularly foot ulcers. Natural products have shown to be effective in treating skin …

Intersex, hermaphroditism, and gonadal plasticity in vertebrates: evolution of the Müllerian duct and Amh/Amhr2 signaling

MC Adolfi, RT Nakajima, RH Nóbrega… - Annual review of …, 2019 - annualreviews.org
In vertebrates, sex organs are generally specialized to perform a male or female reproductive
role. Acquisition of the Müllerian duct, which gives rise to the oviduct, together with …

[HTML][HTML] From inflammation to cutaneous repair: Topical application of lupeol improves skin wound healing in rats by modulating the cytokine levels, NF-κB, Ki-67 …

…, R Kiomi Takahira, R Henrique Nóbrega… - International Journal of …, 2020 - mdpi.com
Skin wound healing is a highly complex event that involves different mediators at the cellular
and molecular level. Lupeol has been reported to possess different biological activities, …

ceRNA crosstalk mediated by ncRNAs is a novel regulatory mechanism in fish sex determination and differentiation

…, F Huang, W You, A Poetsch, RH Nóbrega… - Genome …, 2022 - genome.cshlp.org
Competing endogenous RNAs (ceRNAs) are vital regulators of gene networks in mammals.
The involvement of noncoding RNAs (ncRNAs) as ceRNA in genotypic sex determination (…

Thyroid hormone actions on male reproductive system of teleost fish

…, M da Silva Rodrigues, HR Habibi, RH Nóbrega - General and …, 2018 - Elsevier
Thyroid hormones (THs) play important roles in the regulation of many biological processes
of vertebrates, such as growth, metabolism, morphogenesis and reproduction. An increasing …