[HTML][HTML] A commercial probiotic induces tolerogenic and reduces pathogenic responses in experimental autoimmune encephalomyelitis

…, M Ponce-Alonso, M Castillo, R Lebrón-Galán… - Cells, 2020 - mdpi.com
Previous studies in experimental autoimmune encephalomyelitis (EAE) models have shown
that some probiotic bacteria beneficially impact the development of this experimental …

Hyperglycemia in stroke impairs polarization of monocytes/macrophages to a protective noninflammatory cell type

…, A Othman, T Fleming, R Lebrón-Galán… - Journal of …, 2016 - Soc Neuroscience
Hyperglycemia is common in patients with acute stroke, even in those without preexisting
diabetes, and denotes a bad outcome. However, the mechanisms underlying the detrimental …

[HTML][HTML] The proportion of myeloid-derived suppressor cells in the spleen is related to the severity of the clinical course and tissue damage extent in a murine model of …

…, A Alonso-Gómez, E Moñivas, R Lebrón-Galán… - Neurobiology of …, 2020 - Elsevier
Multiple Sclerosis (MS) is the second cause of paraplegia among young adults, after all types
of CNS traumatic lesions. In its most frequent relapsing-remitting form, the severity of the …

Myeloid‐derived suppressor cells support remyelination in a murine model of multiple sclerosis by promoting oligodendrocyte precursor cell survival, proliferation, and …

…, B Fernández‐Gómez, R LebrónGalán… - Glia, 2021 - Wiley Online Library
The most frequent variant of multiple sclerosis (MS) is the relapsing–remitting form,
characterized by symptomatic phases followed by periods of total/partial recovery. Hence, it is …

[HTML][HTML] Central and peripheral myeloid-derived suppressor cell-like cells are closely related to the clinical severity of multiple sclerosis

MC Ortega, R Lebrón-Galán, I Machín-Díaz… - Acta …, 2023 - Springer
Multiple sclerosis (MS) is a highly heterogeneous demyelinating disease of the central
nervous system (CNS) that needs for reliable biomarkers to foresee disease severity. Recently, …

[HTML][HTML] The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-β treatment in a murine model of multiple sclerosis

C Melero-Jerez, M Suardíaz, R Lebrón-Galán… - Neurobiology of …, 2019 - Elsevier
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the human central
nervous system (CNS), mainly affecting young adults. Among the immunomodulatory disease …

Anosmin-1 over-expression increases adult neurogenesis in the subventricular zone and neuroblast migration to the olfactory bulb

…, D Díaz, I Sánchez-Vera, R Lebrón-Galán… - Brain Structure and …, 2016 - Springer
New subventricular zone (SVZ)-derived neuroblasts that migrate via the rostral migratory
stream are continuously added to the olfactory bulb (OB) of the adult rodent brain. Anosmin-1 (…

[HTML][HTML] The selective loss of purkinje cells induces specific peripheral immune alterations

C Del Pilar, R Lebrón-Galán, E Pérez-Martín… - Frontiers in Cellular …, 2021 - frontiersin.org
The progression of neurodegenerative diseases is reciprocally associated with impairments
in peripheral immune responses. We investigated different contexts of selective …

[HTML][HTML] Graphene oxide films as a novel tool for the modulation of myeloid-derived suppressor cell activity in the context of multiple sclerosis

C Camacho-Toledano, I Machín-Díaz, R Lebrón-Galán… - Nanoscale, 2024 - pubs.rsc.org
Despite the pharmacological arsenal approved for Multiple Sclerosis (MS), there are
treatment-reluctant patients for whom cell therapy appears as the only therapeutic alternative. …

[PDF][PDF] Intracerebellar injection of monocytic immature myeloid cells prevents the adverse effects caused by stereotactic surgery in a model of cerebellar …

…, L del Pozo-Filíu, R Lebrón-Galán… - Journal of …, 2024 - Springer
Background Myeloid-derived suppressor cells (MDSCs) constitute a recently discovered
bone-marrow-derived cell type useful for dealing with neuroinflammatory disorders. However, …