BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was
confirmed in Brazil in February 2020, the first cases were followed by an increase in the number …

The rapid and continuous spread of SARS-CoV-2, responsible for COVID-19, has been
challenging global health systems and many strategies have been proposed to face the COVID-…

Pathogens (bacteria, fungus and virus) are becoming a potential threat to the health of
human beings and environment worldwide. They widely exist in the environment, with …

In March 2020, WHO declared a pandemic state due to SARS-CoV-2 having spread.
TaqMan-based real-time RT-qPCR is currently the gold standard for COVID-19 diagnosis. However…

Background The efficacy of convalescent plasma (CP), an alternative for the treatment of
COVID‐19, depends on high titers of neutralizing antibodies (nAbs), but assays for quantifying …

SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the cysteine-protease
activity, facilitating cleavage of the viral polypeptide chain, PLpro has the additional …

The risk of contamination and dissemination by SARS-CoV-2 has a strong link with nasal,
oral and pharyngeal cavities. Recently, our research group observed the promising …

Although first considered a benign infection, recent studies have disclosed severe and
potentially lethal inflammatory manifestations of COVID-19 in children. We report the case of a 4-…

Introduction Considering the likely need for the development of novel effective vaccines
adapted to emerging relevant CoV-2 variants, the increasing knowledge of epitope recognition …

Coronavirus disease-2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus
infection is a major global public health concern affecting millions of people worldwide. The …