LL-37 is the only cathelicidin-derived polypeptide found in humans. Its eclectic function
makes this peptide one of the most intriguing chemical defense agents, with crucial roles in …

INTRODUCTION Hundreds of cellular proteins are modified by posttranslational S-acylation
of cysteines, commonly known as protein palmitoylation. Unlike other lipid attachments, …

Phospholamban (PLN) is an essential regulator of cardiac muscle contractility. The
homopentameric assembly of PLN is the reservoir for active monomers that, upon deoligomerization …

Phospholamban (PLN) is a type II membrane protein that inhibits the sarcoplasmic reticulum
Ca 2+ -ATPase (SERCA), thereby regulating calcium homeostasis in cardiac muscle. In …

The membrane protein complex between the sarcoplasmic reticulum Ca 2+ -ATPase (SERCA)
and phospholamban (PLN) controls Ca 2+ transport in cardiomyocytes, thereby …

Antigens displayed on self-assembling nanoparticles can stimulate strong immune responses
and have been playing an increasingly prominent role in structure-based vaccines. …

Phospholamban (PLN) and sarcolipin (SLN) are two single-pass membrane proteins that
regulate Ca 2+ -ATPase (SERCA), an ATP-driven pump that translocates calcium ions into the …

In this chapter, we summarize the isotopic labeling strategies used to obtain high-quality
solution and solid-state NMR spectra of biological samples, with emphasis on integral …

Phospholamban (PLN) regulates calcium translocation within cardiac myocytes by shifting
sarco(endo)plasmic reticulum Ca 2+ -ATPase (SERCA) affinity for calcium. Although the …

Lineage-based vaccine design is an attractive approach for eliciting broadly neutralizing
antibodies (bNAbs) against HIV-1. However, most bNAb lineages studied to date have features …