Mobile transposable elements (TEs) not only participate in genome evolution but also
threaten genome integrity. In healthy cells, TEs that encode all of the components that are …

Background It is apparent that genomes harbor much structural variation that is largely
undetected for technical reasons. Such variation can cause artifacts when short-read sequencing …

In plants, aerial organs originate continuously from stem cells in the center of the shoot apical
meristem. Descendants of stem cells in the subepidermal layer are progenitors of germ …

Long noncoding RNAs (lncRNAs) are understudied and underannotated in plants. In mammals,
lncRNA loci are nearly as ubiquitous as protein-coding genes, and their expression is …

Background The repetitive content of the genome, once considered to be “junk DNA”, is in
fact an essential component of genomic architecture and evolution. In this study, we used the …

The National Institute on Drug Abuse (NIDA) is the sole producer of Cannabis for research
purposes in the United States, including medical investigation. Previous research established …

… We thank Bob Schmitz and Daniel Zilberman for comments on the manuscript and Rahul
Pisupati’s thesis. Bisulfite sequencing was performed by the Next Generation Sequencing …

Large-scale studies such as the Arabidopsis thaliana ‘1,001 Genomes’ Project require routine
genotyping of stocks to avoid sample contamination. To genotype samples efficiently and …

Whole-genome bisulfite sequencing (WGBS) is the standard method for profiling DNA
methylation at single-nucleotide resolution. Different tools have been developed to extract …

Background It is apparent that genomes harbor massive amounts of structural variation, and
that this variation has largely gone undetected for technical reasons. In addition to being …