INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Migraine is a debilitating neurological disorder affecting around one in seven people worldwide,
but its molecular mechanisms remain poorly understood. There is some debate about …

Previous genome-wide association studies (GWASs) of stroke — the second leading cause
of death worldwide — were conducted predominantly in populations of European ancestry 1 …

Background Various genome-wide association studies (GWAS) have been done in ischaemic
stroke, identifying a few loci associated with the disease, but sample sizes have been …

Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex
heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (…

Migraine is the most common brain disorder, affecting approximately 14% of the adult
population, but its molecular mechanisms are poorly understood. We report the results of a meta-…

Background and Purpose— The contribution of genetics to stroke risk, and whether this differs
for different stroke subtypes, remainsuncertain. Genomewide complex trait analysis allows …

Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …

Migraine without aura is the most common form of migraine, characterized by recurrent
disabling headache and associated autonomic symptoms. To identify common genetic variants …