Background Modifiable vascular and lifestyle-related risk factors have been associated with
dementia risk in observational studies. In the Finnish Geriatric Intervention Study to Prevent …

To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D),
we conducted a meta-analysis of genetic variants on the Metabochip, including …

The relation of self-selected leisure-time physical activity (LTPA) to first major coronary heart
disease (CHD) events and overall mortality was studied in 12 138 middle-aged men …

Background Previous studies have suggested that higher levels of regular physical activity
and cardiorespiratory fitness are associated with a reduced risk of coronary heart disease. …

OBJECTIVE—Little is known about the association of leisure-time physical activity (LTPA) and
cardiorespiratory fitness with development of the metabolic syndrome, which predisposes …

Purpose The cross-sectional associations of leisure-time physical activity (LTPA) and
cardiorespiratory fitness with the metabolic syndrome (MS) were investigated in a population-…

Objective Mild hypoandrogenism in men is associated with features of the metabolic syndrome,
but the association with the metabolic syndrome itself using an accepted definition has …

Background Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and
Disability (FINGER) is a multi-center, randomized, controlled trial ongoing in Finland. Materials …

Loss-of-function mutations protective against human disease provide in vivo validation of
therapeutic targets 1 , 2 , 3 , but none have yet been described for type 2 diabetes (T2D). …

BACKGROUND We investigated the association of cholesterol concentrations in serum
high density lipoprotein (HDL) and its subfractions HDL2 and HDL3 with the risk of acute …