User profiles for Raja Sekhar Nirujogi
 | Raja Sekhar NirujogiMRC- Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK Verified email at dundee.ac.uk Cited by 6443 |
A draft map of the human proteome
The availability of human genome sequence has transformed biomedical research over the
past decade. However, an equivalent map for the human proteome with direct …
past decade. However, an equivalent map for the human proteome with direct …
[HTML][HTML] Loss of C9orf72 enhances autophagic activity via deregulated mTOR and TFEB signaling
The most common cause of the neurodegenerative diseases amyotrophic lateral sclerosis
and frontotemporal dementia is a hexanucleotide repeat expansion in C9orf72. Here we …
and frontotemporal dementia is a hexanucleotide repeat expansion in C9orf72. Here we …
Proteomic analysis of human follicular fluid: a new perspective towards understanding folliculogenesis
Human follicular fluid is a complex body fluid that constitutes the microenvironment of developing
follicles in the ovary. Follicular fluid contains a number of proteins that modulate oocyte …
follicles in the ovary. Follicular fluid contains a number of proteins that modulate oocyte …
[HTML][HTML] Proteomic analysis of human osteoarthritis synovial fluid
L Balakrishnan, RS Nirujogi, S Ahmad… - Clinical proteomics, 2014 - Springer
Background Osteoarthritis is a chronic musculoskeletal disorder characterized mainly by
progressive degradation of the hyaline cartilage. Patients with osteoarthritis often postpone …
progressive degradation of the hyaline cartilage. Patients with osteoarthritis often postpone …
[HTML][HTML] Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
…, SM Lange, V Dee Cesare, SP Matthews, RS Nirujogi… - PloS one, 2021 - journals.plos.org
Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and
plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein…
plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein…
Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover
Memory formation is believed to result from changes in synapse strength and structure. While
memories may persist for the lifetime of an organism, the proteins and lipids that make up …
memories may persist for the lifetime of an organism, the proteins and lipids that make up …
[HTML][HTML] Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients
…, M Bhattacharjee, S Ahmad, RS Nirujogi… - Clinical proteomics, 2014 - Springer
… Raja Sekhar Nirujogi … Sartaj Ahmad and Raja Sekhar Nirujogi contributed equally to
this article. … Lavanya Balakrishnan, Raja Sekhar Nirujogi, … Akhilesh Pandey …
this article. … Lavanya Balakrishnan, Raja Sekhar Nirujogi, … Akhilesh Pandey …
Ubiquilin 2 modulates ALS/FTD-linked FUS–RNA complex dynamics and stress granule formation
The ubiquitin-like protein ubiquilin 2 (UBQLN2) has been genetically and pathologically
linked to the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and …
linked to the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and …
SILAC‐based quantitative proteomic analysis of gastric cancer secretome
…, L Balakrishnan, N Syed, NR Sekhar… - PROTEOMICS …, 2013 - Wiley Online Library
Purpose Gastric cancer is a commonly occurring cancer in A sia and one of the leading causes
of cancer deaths. However, there is no reliable blood‐based screening test for this cancer…
of cancer deaths. However, there is no reliable blood‐based screening test for this cancer…
Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes
Complementing genome sequence with deep transcriptome and proteome data could enable
more accurate assembly and annotation of newly sequenced genomes. Here, we provide …
more accurate assembly and annotation of newly sequenced genomes. Here, we provide …