User profiles for Rajib Sengupta

RAJIB SENGUPTA

Associate Professor, Amity Institute of Biotechnology, Kolkata
Verified email at kol.amity.edu
Cited by 1764

Novel cellulases from an extremophilic filamentous fungi Penicillium citrinum: production and characterization

T Dutta, R Sahoo, R Sengupta, SS Ray… - Journal of Industrial …, 2008 - academic.oup.com
The enzymatic hydrolysis of cellulose has potential economical and environment-friendly
applications. Therefore, discovery of new extremophilic cellulases is essential to meet the …

Thioredoxin and Thioredoxin Reductase in Relation to Reversible S-Nitrosylation

R Sengupta, A Holmgren - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Nitric oxide (NO) regulates a diverse range of cellular processes, including
vasodilation, neurotransmission, and antimicrobial and anti-tumor activities. S-nitrosylation with …

Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase

I Pader, R Sengupta, M Cebula, J Xu… - Proceedings of the …, 2014 - National Acad Sciences
Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain
containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member …

The use of thiols by ribonucleotide reductase

A Holmgren, R Sengupta - Free Radical Biology and Medicine, 2010 - Elsevier
Ribonucleotide reductase (RNR) catalyzes the rate-limiting de novo synthesis of 2′-deoxyribonucleotides
from the corresponding ribonucleotides and thereby provides balanced …

The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity

…, AK Roos, SJ Montano, R Sengupta… - Biochemical …, 2011 - portlandpress.com
Human GLRX5 (glutaredoxin 5) is an evolutionarily conserved thiol–disulfide oxidoreductase
that has a direct role in the maintenance of normal cytosolic and mitochondrial iron …

Thioredoxin Catalyzes the Denitrosation of Low-Molecular Mass and Protein S-Nitrosothiols

R Sengupta, SW Ryter, BS Zuckerbraun, E Tzeng… - Biochemistry, 2007 - ACS Publications
While most proteins have critical thiols whose oxidation affects their activity, it has been
suggested that S-nitrosation and denitrosation of cellular thiols are fundamental processes …

[HTML][HTML] Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase

R Sengupta, A Holmgren - World journal of biological chemistry, 2014 - ncbi.nlm.nih.gov
Ribonucleotide reductase (RNR), the rate-limiting enzyme in DNA synthesis, catalyzes reduction
of the different ribonucleotides to their corresponding deoxyribonucleotides. The crucial …

The role of thioredoxin in the regulation of cellular processes by S-nitrosylation

R Sengupta, A Holmgren - Biochimica et Biophysica Acta (BBA)-General …, 2012 - Elsevier
BACKGROUND: S-nitrosylation (or S-nitrosation) by Nitric Oxide (NO), ie, the covalent
attachment of a NO group to a cysteine thiol and formation of S-nitrosothiols (RSN=O or RSNO), …

Glutathione: Role in oxidative/nitrosative stress, antioxidant defense, and treatments

…, S Chakraborty, E Sircar, S Dutta, R Sengupta - …, 2021 - Wiley Online Library
Glutathione (GSH) is the most abundant cellular tripeptide (L‐γ‐glutamate‐L‐cysteinyl‐glycine)
which is as critical as oxygen and water. This low molecular mass antioxidant has a very …

[HTML][HTML] Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites

…, J Li, Q Jiang, M Zhang, L Wang, R Sengupta… - Acta …, 2021 - Springer
The mechanisms by which parkin protects the adult human brain from Parkinson disease
remain incompletely understood. We hypothesized that parkin cysteines participate in redox …