User profiles for Rajneesh Pathania
Rajneesh PathaniaNIEHS Verified email at nih.gov Cited by 821 |
[HTML][HTML] DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis
Mammary stem/progenitor cells (MaSCs) maintain self-renewal of the mammary epithelium
during puberty and pregnancy. DNA methylation provides a potential epigenetic mechanism …
during puberty and pregnancy. DNA methylation provides a potential epigenetic mechanism …
Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth
Recently, impressive technical advancements have been made in the isolation and validation
of mammary stem cells and cancer stem cells (CSC), but the signaling pathways that …
of mammary stem cells and cancer stem cells (CSC), but the signaling pathways that …
[PDF][PDF] Multi-omic profiling reveals dynamics of the phased progression of pluripotency
Pluripotency is highly dynamic and progresses through a continuum of pluripotent stem cell
states. The two states that bookend the pluripotency continuum, naive and primed, are well …
states. The two states that bookend the pluripotency continuum, naive and primed, are well …
The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival
GPR109A, a G-protein–coupled receptor, is activated by niacin and butyrate. Upon activation
in colonocytes, GPR109A potentiates anti-inflammatory pathways, induces apoptosis, and …
in colonocytes, GPR109A potentiates anti-inflammatory pathways, induces apoptosis, and …
[HTML][HTML] Cystic pulmonary hydatidosis
M Sarkar, R Pathania, A Jhobta, BR Thakur… - Lung India, 2016 - journals.lww.com
Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by the larval stages of
the cestode Echinococcus granulosus. Worldwide, pulmonary hydatid cyst is a significant …
the cestode Echinococcus granulosus. Worldwide, pulmonary hydatid cyst is a significant …
RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal
AE Bridges, S Ramachandran, R Pathania, U Parwal… - Cancer research, 2020 - AACR
… Rajneesh Pathania; Rajneesh Pathania … Pathania contributed equally to this article. …
[HTML][HTML] The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis
R Sangani, S Periyasamy-Thandavan, R Pathania… - Stem cell …, 2015 - Elsevier
Vitamin C is an antioxidant that plays a vital role in various biological processes including
bone formation. Previously, we reported that vitamin C is transported into bone marrow stromal …
bone formation. Previously, we reported that vitamin C is transported into bone marrow stromal …
Molecular mechanism of SLC5A8 inactivation in breast cancer
S Elangovan, R Pathania… - … and cellular biology, 2013 - Taylor & Francis
SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of
cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the …
cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the …
[PDF][PDF] Pulmonary hamartoma: Case report and brief review of literature
N Raina, V Kaushal, R Pathania, A Rana - Clin Cancer Investig J, 2016 - ccij-online.org
Pulmonary hamartoma are benign, well‑circumscribed single nodule in the lung parenchyma.
They are composed of an abnormal mixture of epithelial and mesenchymal elements. …
They are composed of an abnormal mixture of epithelial and mesenchymal elements. …
Combination of DNMT and HDAC inhibitors reprogram cancer stem cell signaling to overcome drug resistance
In recent years, impressive technical advancements have been made in the isolation and
validation of the mammary stem cells (MaSCs) and cancer stem cells (CSCs). However, the …
validation of the mammary stem cells (MaSCs) and cancer stem cells (CSCs). However, the …