User profiles for Rajneesh Pathania

Rajneesh Pathania

NIEHS
Verified email at nih.gov
Cited by 821

[HTML][HTML] DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

R Pathania, S Ramachandran, S Elangovan… - Nature …, 2015 - nature.com
Mammary stem/progenitor cells (MaSCs) maintain self-renewal of the mammary epithelium
during puberty and pregnancy. DNA methylation provides a potential epigenetic mechanism …

Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth

R Pathania, S Ramachandran, G Mariappan, P Thakur… - Cancer research, 2016 - AACR
Recently, impressive technical advancements have been made in the isolation and validation
of mammary stem cells and cancer stem cells (CSC), but the signaling pathways that …

[PDF][PDF] Multi-omic profiling reveals dynamics of the phased progression of pluripotency

P Yang, SJ Humphrey, S Cinghu, R Pathania… - Cell Systems, 2019 - cell.com
Pluripotency is highly dynamic and progresses through a continuum of pluripotent stem cell
states. The two states that bookend the pluripotency continuum, naive and primed, are well …

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival

S Elangovan, R Pathania, S Ramachandran, S Ananth… - Cancer research, 2014 - AACR
GPR109A, a G-protein–coupled receptor, is activated by niacin and butyrate. Upon activation
in colonocytes, GPR109A potentiates anti-inflammatory pathways, induces apoptosis, and …

[HTML][HTML] Cystic pulmonary hydatidosis

M Sarkar, R Pathania, A Jhobta, BR Thakur… - Lung India, 2016 - journals.lww.com
Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by the larval stages of
the cestode Echinococcus granulosus. Worldwide, pulmonary hydatid cyst is a significant …

RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal

AE Bridges, S Ramachandran, R Pathania, U Parwal… - Cancer research, 2020 - AACR
Rajneesh Pathania; Rajneesh PathaniaPathania contributed equally to this article. …

[HTML][HTML] The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis

R Sangani, S Periyasamy-Thandavan, R Pathania… - Stem cell …, 2015 - Elsevier
Vitamin C is an antioxidant that plays a vital role in various biological processes including
bone formation. Previously, we reported that vitamin C is transported into bone marrow stromal …

Molecular mechanism of SLC5A8 inactivation in breast cancer

S Elangovan, R Pathania… - … and cellular biology, 2013 - Taylor & Francis
SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of
cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the …

[PDF][PDF] Pulmonary hamartoma: Case report and brief review of literature

N Raina, V Kaushal, R Pathania, A Rana - Clin Cancer Investig J, 2016 - ccij-online.org
Pulmonary hamartoma are benign, well‑circumscribed single nodule in the lung parenchyma.
They are composed of an abnormal mixture of epithelial and mesenchymal elements. …

Combination of DNMT and HDAC inhibitors reprogram cancer stem cell signaling to overcome drug resistance

R Pathania, RB Kolhe, S Ramachandran, G Mariappan… - Cancer Research, 2016 - AACR
In recent years, impressive technical advancements have been made in the isolation and
validation of the mammary stem cells (MaSCs) and cancer stem cells (CSCs). However, the …