The mechanical properties of tumors and the tumor environment provide important
information for the progression and characterization of cancer. Tumors are surrounded by an …

In the early stages of metastasis, cancer cells exit the primary tumor and enter the vasculature.
Although most studies have focused on the tumor invasive front, cancer cells from the …

The shape of cellular membranes is highly regulated by a set of conserved mechanisms
that can be manipulated by bacterial pathogens to infect cells. Remodeling of the plasma …

Tumor initiation and growth is associated with significant changes in the surrounding tissue.
During carcinoma progression, a global stiffening of the extracellular matrix is observed and …

The barrier function of epithelia is one of the cornerstones of the body plan organization of
metazoans. It relies on the polarity of epithelial cells which organizes along the apico-basal …

Cell migration is a process that ensures correct cell localization and function in development
and homeostasis. In disease such as cancer, cells acquire an upregulated migratory …

Metastasis is a hallmark of cancer and the leading cause of mortality among cancer patients.
Cancer, in its most deadly form, is thus not only a disease of uncontrolled cell growth but …

The shape of cellular membranes is highly regulated by a set of conserved mechanisms.
These mechanisms can be manipulated by bacterial pathogens to infect cells. Human …

Carcinoma development is a multistep process, in which accumulation of genetic alterations
promotes the sustained proliferation and altered differentiation of epithelial cells. Metastasis …

… Ralitza Staneva is first author on ‘ Cancer cells in the tumor core exhibit spatially coordinated
migration patterns ’, published in JCS. Ralitza is a postdoc in the lab of Danijela Matic …