User profiles for Rameshwar Patil
Rameshwar PatilAssociate Professor, Dept of Basic Science, Division of Cancer Science, Loma Linda … Verified email at llu.edu Cited by 1953 |
[HTML][HTML] Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy
Brain glioma treatment with checkpoint inhibitor antibodies to cytotoxic T-lymphocyte-associated
antigen 4 (a-CTLA-4) and programmed cell death-1 (a-PD-1) was largely unsuccessful …
antigen 4 (a-CTLA-4) and programmed cell death-1 (a-PD-1) was largely unsuccessful …
Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?
…, V Yamamoto, B Khalsa, JY Ljubimova, H Ding, R Patil… - Neuroimage, 2011 - Elsevier
Nanotechnology is the design and assembly of submicroscopic devices called nanoparticles,
which are 1–100 nm in diameter. Nanomedicine is the application of nanotechnology for …
which are 1–100 nm in diameter. Nanomedicine is the application of nanotechnology for …
Inhibition of brain tumor growth by intravenous poly(β-l-malic acid) nanobioconjugate with pH-dependent drug release
H Ding, S Inoue, AV Ljubimov, R Patil… - Proceedings of the …, 2010 - National Acad Sciences
Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple
sclerosis, or tumors should be possible with drug delivery through blood–brain barrier (BBB) or …
sclerosis, or tumors should be possible with drug delivery through blood–brain barrier (BBB) or …
[HTML][HTML] Cellular delivery of doxorubicin via pH-controlled hydrazone linkage using multifunctional nano vehicle based on poly (β-L-malic acid)
Doxorubicin (DOX) is currently used in cancer chemotherapy to treat many tumors and
shows improved delivery, reduced toxicity and higher treatment efficacy when being part of …
shows improved delivery, reduced toxicity and higher treatment efficacy when being part of …
Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly (β-L-malic acid)
Purpose Temozolomide (TMZ) is a pro-drug releasing a DNA alkylating agent that is the
most effective drug to treat glial tumors when combined with radiation. TMZ is toxic, and …
most effective drug to treat glial tumors when combined with radiation. TMZ is toxic, and …
[HTML][HTML] HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug
H Ding, PR Gangalum, A Galstyan, I Fox, R Patil… - … , Biology and Medicine, 2017 - Elsevier
HER2+ breast cancer is one of the most aggressive forms of breast cancer. The new polymalic
acid-based mini nanodrug copolymers are synthesized and specifically characterized to …
acid-based mini nanodrug copolymers are synthesized and specifically characterized to …
MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain
Differential diagnosis of brain magnetic resonance imaging (MRI) enhancement(s) remains
a significant problem, which may be difficult to resolve without biopsy, which can be often …
a significant problem, which may be difficult to resolve without biopsy, which can be often …
Blockade of a laminin-411–notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment cross-talk
… Rameshwar Patil; Rameshwar Patil … Patil …
[HTML][HTML] Coarse particulate matter (PM2.5–10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains
Air pollution is linked to brain inflammation, which accelerates tumorigenesis and
neurodegeneration. The molecular mechanisms that connect air pollution with brain pathology are …
neurodegeneration. The molecular mechanisms that connect air pollution with brain pathology are …
Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly (β-L-malic acid)
…, ML Penichet, KA Wawrowsky, R Patil… - Journal of Controlled …, 2007 - Elsevier
Tumor-specific targeting using achievements of nanotechnology is a mainstay of increasing
efficacy of anti-tumor drugs. To improve drug targeting we covalently conjugated for the first …
efficacy of anti-tumor drugs. To improve drug targeting we covalently conjugated for the first …