Brain glioma treatment with checkpoint inhibitor antibodies to cytotoxic T-lymphocyte-associated
antigen 4 (a-CTLA-4) and programmed cell death-1 (a-PD-1) was largely unsuccessful …

Nanotechnology is the design and assembly of submicroscopic devices called nanoparticles,
which are 1–100 nm in diameter. Nanomedicine is the application of nanotechnology for …

Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple
sclerosis, or tumors should be possible with drug delivery through blood–brain barrier (BBB) or …

Doxorubicin (DOX) is currently used in cancer chemotherapy to treat many tumors and
shows improved delivery, reduced toxicity and higher treatment efficacy when being part of …

Purpose Temozolomide (TMZ) is a pro-drug releasing a DNA alkylating agent that is the
most effective drug to treat glial tumors when combined with radiation. TMZ is toxic, and …

HER2+ breast cancer is one of the most aggressive forms of breast cancer. The new polymalic
acid-based mini nanodrug copolymers are synthesized and specifically characterized to …

Differential diagnosis of brain magnetic resonance imaging (MRI) enhancement(s) remains
a significant problem, which may be difficult to resolve without biopsy, which can be often …

… Rameshwar Patil; Rameshwar Patil … Patil …

Air pollution is linked to brain inflammation, which accelerates tumorigenesis and
neurodegeneration. The molecular mechanisms that connect air pollution with brain pathology are …

Tumor-specific targeting using achievements of nanotechnology is a mainstay of increasing
efficacy of anti-tumor drugs. To improve drug targeting we covalently conjugated for the first …