User profiles for Rani Sarkis
Rani Sarkis MD, MSc.Brigham and Women's Hospital, Harvard Medical School Verified email at partners.org Cited by 1939 |
[HTML][HTML] Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease
The extent of microglial heterogeneity in humans remains a central yet poorly explored question
in light of the development of therapies targeting this cell type. Here, we investigate the …
in light of the development of therapies targeting this cell type. Here, we investigate the …
Association of epileptiform abnormalities and seizures in Alzheimer disease
Objective To examine the relationship between scalp EEG biomarkers of hyperexcitability in
Alzheimer disease (AD) and to determine how these electric biomarkers relate to the clinical …
Alzheimer disease (AD) and to determine how these electric biomarkers relate to the clinical …
Expert-level automated sleep staging of long-term scalp electroencephalography recordings using deep learning
Study Objectives Develop a high-performing, automated sleep scoring algorithm that can be
applied to long-term scalp electroencephalography (EEG) recordings. Methods Using a …
applied to long-term scalp electroencephalography (EEG) recordings. Methods Using a …
Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Review of Psychiatric Phenotypes and Management Considerations: A Report of the American Neuropsychiatric …
Objective: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune
disorder characterized by prominent neuropsychiatric symptoms. Given the nature of its …
disorder characterized by prominent neuropsychiatric symptoms. Given the nature of its …
Clinical and neurophysiologic characteristics of unprovoked seizures in patients diagnosed with dementia
Seizures are a common comorbid condition in patients with dementia, but their characteristics
have been poorly described. The authors performed a retrospective chart review using ICD…
have been poorly described. The authors performed a retrospective chart review using ICD…
Autonomic changes following generalized tonic clonic seizures: an analysis of adult and pediatric patients with epilepsy
Objective Sudden unexpected death in epilepsy (SUDEP) is the most common cause of
mortality directly related to epilepsy. Its incidence is higher in adult patients and its …
mortality directly related to epilepsy. Its incidence is higher in adult patients and its …
Seizure outcomes following multilobar epilepsy surgery
Purpose: Outcomes following unilobar surgeries for refractory epilepsy have been well
described. However, little is known about long‐term seizure outcomes following multilobar …
described. However, little is known about long‐term seizure outcomes following multilobar …
[HTML][HTML] Prospective study of a multimodal convulsive seizure detection wearable system on pediatric and adult patients in the epilepsy monitoring unit
…, F Mohammadpour-Touserkani, RA Sarkis… - Frontiers in …, 2021 - frontiersin.org
Background: Using machine learning to combine wrist accelerometer (ACM) and electrodermal
activity (EDA) has been shown effective to detect primarily and secondarily generalized …
activity (EDA) has been shown effective to detect primarily and secondarily generalized …
Noninvasive detection of hippocampal epileptiform activity on scalp electroencephalogram
M Abou Jaoude, CS Jacobs, RA Sarkis, J Jing… - JAMA …, 2022 - jamanetwork.com
Importance The hippocampus is a highly epileptogenic brain region, yet over 90% of hippocampal
epileptiform activity (HEA) cannot be identified on scalp electroencephalogram (EEG) …
epileptiform activity (HEA) cannot be identified on scalp electroencephalogram (EEG) …
Video-based detection of generalized tonic-clonic seizures using deep learning
Y Yang, RA Sarkis, R El Atrache… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Timely detection of seizures is crucial to implement optimal interventions, and may help
reduce the risk of sudden unexpected death in epilepsy (SUDEP) in patients with generalized …
reduce the risk of sudden unexpected death in epilepsy (SUDEP) in patients with generalized …