User profiles for Ranran Kong

Ranran Kong

Icahn School of Medicine at Mount Sinai; Xi'an Jiaotong University
Verified email at mssm.edu
Cited by 507

Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer

AS Patel, S Yoo, R Kong, T Sato, A Sinha, S Karam… - Science …, 2021 - science.org
Comprehensive genomic analyses of small cell lung cancer (SCLC) have revealed frequent
mutually exclusive genomic amplification of MYC family members. Hence, it has been long …

[HTML][HTML] The crucial role of miR-126 on suppressing progression of esophageal cancer by targeting VEGF-A

R Kong, Y Ma, J Feng, S Li, W Zhang, J Jiang… - Cellular & Molecular …, 2016 - Springer
Background miR-126 is a key regulator of oncogenic processes. It is functionally linked to
cellular proliferation, survival and migration. Vascular endothelial growth factor A (VEGF-A), …

[HTML][HTML] Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression

…, D Chavez, E Lee, AS Patel, T Sato, R Kong… - Nature …, 2022 - nature.com
Here we focus on the molecular characterization of clinically significant histological subtypes
of early-stage lung adenocarcinoma (esLUAD), which is the most common histological …

[HTML][HTML] SphK1 promotes development of non‑small cell lung cancer through activation of STAT3

Y Ma, X Xing, R Kong, C Cheng… - International …, 2021 - spandidos-publications.com
Sphingosine kinase1 (SphK1) is an oncogenic enzyme that regulates tumor cell apoptosis,
proliferation and survival. SphK1 has been reported to promote the development of non‑…

Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation

…, L Xie, X Yu, C Liu, H Dong, W Lu, R Kong - … and Biophysical Research …, 2021 - Elsevier
Hyperglycemia-induced podocyte damage contributes to the onset of diabetic nephropathy,
a severe complication of diabetes. Perilipin 5 (Plin5) exerts a vital role in numerous …

Co-pyrolysis of chitin with nitrogen carriers: Kinetics, product characterization and bio-oil analysis

J Liu, S Liu, A Zhao, D Bi, D Yao, R Kong - Journal of Analytical and Applied …, 2023 - Elsevier
Considering the depletion of fossil fuels and the cumbersome traditional synthesis process of
chemical compounds containing nitrogen, there is increased interest in direct production of …

MicroRNA-384 represses the growth and invasion of non-small-cell lung cancer by targeting astrocyte elevated gene-1/Wnt signaling

…, J Zhang, C Cheng, X Zhang, J Feng, R Kong - Biomedicine & …, 2017 - Elsevier
Dysregulation of microRNA (miRNA) expression is a critical event in the development and
progression of non-small-cell lung cancer (NSCLC). miR-384 has been identified as a novel …

[HTML][HTML] S100A8 and S100A9, both transcriptionally regulated by PU. 1, promote epithelial-mesenchymal transformation (EMT) and invasive growth of dermal …

Z Xu, C Cheng, R Kong, Y Liu, S Wang, Y Ma… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
S100 calcium-binding protein A8 (S100A8) and S100A9 are small molecular weight calcium-binding
regulatory proteins that have been involved in multiple chronic inflammatory …

Silencing of Rab3D suppresses the proliferation and invasion of esophageal squamous cell carcinoma cells

J Zhang, R Kong, L Sun - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Rab3D is a member of the ras-related GTP-binding protein Rab family and was found up-regulated
in several types of cancer. However, little is known about the role of Rab3D in …

[HTML][HTML] Early-stage lung adenocarcinoma MDM2 genomic amplification predicts clinical outcome and response to targeted therapy

…, Y Zou, AS Patel, S Yoo, F Jiang, T Sato, R Kong… - Cancers, 2022 - mdpi.com
Simple Summary Invasive subtypes of lung adenocarcinoma (LUAD) show MDM2
amplification that is associated with poor survival. Mouse double minute 2 (MDM2) is frequently …