The need for new safe and efficacious therapies has led to an increased focus on biologics
produced in mammalian cells. The human cell line HEK293 has bio-synthetic potential for …

Recombinant protein production can cause severe stress on cellular metabolism, resulting
in limited titer and product quality. To investigate cellular and metabolic characteristics …

Deregulation of the protein secretory pathway (PSP) is linked to many hallmarks of cancer,
such as promoting tissue invasion and modulating cell-cell signaling. The collection of …

Since the emergence of modern biotechnology, the production of recombinant pharmaceutical
proteins has been an expanding field with high demand from industry. Pharmaceutical …

Higher eukaryotic cell lines like HEK293 are the preferred hosts for production of therapeutic
proteins requiring human post translational processing. However, recombinant protein …

“A comparison of mRNA levels of the viral element E1A showed significantly (p< 0.05) higher
expression in HEK293 compared to both 293T and Freestyle 293-F. In addition, both 293E …

… our gratitude to Rasool Saghaleyni, whose insight and explanations of biomedical concepts
helped us understand the fundamentals of the texts we have studied. Rasool’s enthusiasm …

… our gratitude to Rasool Saghaleyni, whose insight and explanations of biomedical concepts
helped us understand the fundamentals of the texts we have studied. Rasool’s enthusiasm …

… our gratitude to Rasool Saghaleyni, whose insight and explanations of biomedical concepts
helped us understand the fundamentals of the texts we have studied. Rasool’s enthusiasm …

… Rasool Saghaleyni, Dept Biology and Biological Engineering, Chalmers University of
Technology, Sweden … Johan Rockberg, Magdalena Malm, Rasool Saghaleyni, Niklas Thalén …