The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was
set up to analyze brain measures and genotypes from multiple sites across the world to …

purpose. Diabetic retinopathy (DR) and diabetic nephropathy (DN) are serious microvascular
complications of diabetes mellitus. Correlations between severity of DR and DN and …

The degree to which genetic factors influence brain connectivity is beginning to be understood.
Large-scale efforts are underway to map the profile of genetic effects in various brain …

BACKGROUND: Despite overwhelming evidence that major depression is highly heritable,
recent studies have localized only a single depression-related locus reaching genome-wide …

Combining datasets across independent studies can boost statistical power by increasing
the numbers of observations and can achieve more accurate estimates of effect sizes. This is …

Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease (CKD)
in the industrialized world and accounts for much of the excess mortality in patients with …

The Family Investigation of Nephropathy and Diabetes (FIND) was initiated to map genes
underlying susceptibility to diabetic nephropathy. A total of 11 centers participated under a …

10.7554/eLife.04637.001 Although the past decade has seen tremendous progress in our
understanding of fine-scale recombination, little is known about non-crossover (NCO) gene …